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Nav1.8-IN-5 (Example 1) is a voltage-gated sodium channel Nav1.8 inhibitor. Nav1.8-IN-5 can be used for Nav1.8-mediated diseases, such as pain and pain-related disorders, as well as cardiovascular diseases (such as atrial fibrillation) research[1].
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Nav1.8-IN-6 (Compound 2j) is a novel pyridinone amide Nav1.8 channel inhibitor. The IC50 values in the resting state and semi-activated state are 513.33 and 471.81 nM, respectively. Nav1.8-IN-6 has analgesic activity[1].
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Nav1.8-IN-7 (Example 116) is a selective Nav1.8 inhibitor. Nav1.8-IN-7 shows an inhibition of >50% with 100 nM for Nav1.8. Nav1.8-IN-7 inhibits hERG with an IC50 of 15.6 μM. Nav1.8-IN-7 has the potential for pain research[1].
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Nav1.8-IN-8 (Compound A11) is a Nav1.8 channel inhibitor. Nav1.8-IN-8 may prevent associated diseases mediated by sodium ion channels (NaV)[1].
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NAV2 Human Pre-designed siRNA Set A contains three designed siRNAs for NAV2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NAV3 Human Pre-designed siRNA Set A contains three designed siRNAs for NAV3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NAXD Human Pre-designed siRNA Set A contains three designed siRNAs for NAXD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NAXE Human Pre-designed siRNA Set A contains three designed siRNAs for NAXE gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NB512 (compound 39a) is a dual inhibitor for BET and HDAC, which exhibits a efficient binding affinity with BRD4 bromodomains and HDAC1/2, with EC50s of 100-400 nM. NB512 exhibits an anti-proliferative activity towards cancer cells PaTu8988T and NMC[1].
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NBAS Human Pre-designed siRNA Set A contains three designed siRNAs for NBAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBD-undecanoic acid is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also […]
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NBDY Human Pre-designed siRNA Set A contains three designed siRNAs for NBDY gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBEA Human Pre-designed siRNA Set A contains three designed siRNAs for NBEA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBEAL1 Human Pre-designed siRNA Set A contains three designed siRNAs for NBEAL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBEAL2 Human Pre-designed siRNA Set A contains three designed siRNAs for NBEAL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBI 35965 methanesulfonate is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki value of 4 nM and a pKi value of 8.5. NBI 35965 methanesulfonate does not inhibit CRF2. NBI 35965 methanesulfonate reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC50 values of 7.1 and […]
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NBL1 Human Pre-designed siRNA Set A contains three designed siRNAs for NBL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBN Human Pre-designed siRNA Set A contains three designed siRNAs for NBN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBPF1 Human Pre-designed siRNA Set A contains three designed siRNAs for NBPF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBPF10 Human Pre-designed siRNA Set A contains three designed siRNAs for NBPF10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBPF3 Human Pre-designed siRNA Set A contains three designed siRNAs for NBPF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NBR1 Human Pre-designed siRNA Set A contains three designed siRNAs for NBR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCA029 is a potent and selective homo sapiens caseinolytic protease P (HsClpP) activator with an EC50 of 0.15 μM. NCA029 acts on HsClpP to activate an ATF3-dependent integrative stress response, leading to colon cancer cell death[1].
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NCALD Human Pre-designed siRNA Set A contains three designed siRNAs for NCALD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAM1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCAM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAM2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCAM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAN Human Pre-designed siRNA Set A contains three designed siRNAs for NCAN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAPD2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCAPD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAPD3 Human Pre-designed siRNA Set A contains three designed siRNAs for NCAPD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAPG Human Pre-designed siRNA Set A contains three designed siRNAs for NCAPG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAPG2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCAPG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAPH Human Pre-designed siRNA Set A contains three designed siRNAs for NCAPH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCAPH2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCAPH2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCCRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCCRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCDN Human Pre-designed siRNA Set A contains three designed siRNAs for NCDN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCEH1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCEH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCF1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCF2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCF4 Human Pre-designed siRNA Set A contains three designed siRNAs for NCF4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCK1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NCK2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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