MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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Mifepristone-d6 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mifepristone-d6 is deuterated labeled Mifepristone (HY-13683). Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay[1].

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Milbemycin A4 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity[1]sup>[2].

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Minocycline hydrochloride (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Minocycline (hydrochloride) (Standard) is the analytical standard of Minocycline (hydrochloride). This product is intended for research and analytical applications. Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows […]

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Mirtazapine-d4 hydrochloride | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mirtazapine-d4 hydrochloride is deuterated labeled Mirtazapine (HY-B0352). Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT2, 5-HT3, histamine H1 receptor and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3 and 6.95, respectively[1][2].

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Mito Flipper-TR 27 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mito Flipper-TR 27 is a fluorescent probe for measuring membrane tension in living cells. Mito Flipper-TR 27 accumulates in mitochondria because the strong internal negative membrane potential drives the permanent hydrophobic triphenylphosphine cation across the inner membrane and prevents its release, thus enabling it to be used for tracking mitochondria[1].

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Mito Red | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mito Red is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also […]

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Mito-DK | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mito-DK is a small-molecule fluorescent dye with the capability of crosstalk-free response to polarity and mtDNA as well as mitochondrial morphology. Mito-DK has high photostability, low cytotoxicity, and good mitochondria-targeting properties. Mito-DK can be used for real-time tracking and multidimensional assessing of mitochondria-related pyroptosis in cancer cells[1].

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Mito-PN | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mito-PN is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely […]

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Mito-Rh-S | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC)[1].

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MitoB bromide | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

MitoB bromide is an exomarker of mitochondrial hydrogen peroxide. MitoB bromide is a mitochondria-targeted ratiometric probe, and can be used to measure levels of one major ROS, hydrogen peroxide, within living animals[1][2].

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Mitophagy Compound Library | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mitochondrial autophagy refers to the selective encapsulation and degradation of damaged mitochondria by cells through the autophagy mechanism, thereby maintaining mitochondrial and cellular homeostasis. The concept of mitochondrial autophagy has received extensive attention since it was proposed. Current studies have shown that the mechanisms of mitochondrial autophagy can generally be divided into two categories: Ubiquitin-dependent […]

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Mitoxantrone-d8 dihydrochloride | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Mitoxantrone-d8 dihydrochloride is deuterated labeled Mitoxantrone dihydrochloride (HY-13502A). Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity[1][2][3][4]. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of […]

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MK-1084 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

MK-1084 is a selective KRAS G12C inhibitor that is currently in Phase I clinical trial (NCT05067283). MK-1084 exhibits anticancer activity and can be used either alone or in combination with pembrolizumab (HY-P9902) for cancer research[1].

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MK-6240 | MedChemExpress (MCE) 10 mM * 1 mL  | 99.9%

MedChem Express

MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs[1].

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