MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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Lck-IN-2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Lck-IN-2 (compound 12a) is an inhibitor of Lymphocyte-specific protein tyrosine kinase (Lck) with IC50 of 10.6 nM. Lck-IN-2 reveals efficacy in colon cancer cells with GI50s of 0.24-1.26 μM. Lck-IN-2 exhibits an apoptotic effect in Colo201 cells[1].

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Lck-IN-3 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Lck-IN-3 (compound 7m) is an LCK inhibitor targeting acute lymphoblastic leukemia (ALL) that inhibits LCK phosphorylation. Lck-IN-3 can induce cell cycle arrest in the G2/M phase, leading to apoptosis in ALL cells[1].

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LDL-IN-1 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

LDL-IN-1 (Compound 1) is an antioxidant, and is active against copper mediated LDL oxidation (IC50 = 52 μM). LDL-IN-1 is also an Acyl-CoA:cholesterol acyltransferase-1 and -2 (ACAT-1/2) inhibitor, with IC50s of 60 μM. LDL-IN-1 can be used for anti-atherosclerotic research[1].

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LDL-IN-4 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

LDL-IN-4 (Compound 2) inhibits human acyl-CoA:cholesterol acyltransferase-1 and -2 activities. LDL-IN-4 inhibits copper-mediated low density lipoprotein (LDL) oxidation, with an IC50 of 3 μM. LDL-IN-4 has anti-atherosclerotic biological activity[1].

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Lectin from Helix pomatia, biotin conjugate | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Helix pomatia lectin, biotin conjugate, is a carbohydrate-binding protein that is widely found in fungi, plants, and animals. Helix pomatia lectin, biotin conjugate is commonly used for characterizing, imaging, or targeting glycoconjugates, and is also a very useful tool for glycomics analysis[1].

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Ledipasvir-d6 hydrochloride | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Ledipasvir-d6 hydrochloride is deuterated labeled Ledipasvir acetone (HY-15602A). Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.

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