MedChem Express
JADE2 Human Pre-designed siRNA Set A contains three designed siRNAs for JADE2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JADE3 Human Pre-designed siRNA Set A contains three designed siRNAs for JADE3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAG1 Human Pre-designed siRNA Set A contains three designed siRNAs for JAG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAG2 Human Pre-designed siRNA Set A contains three designed siRNAs for JAG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAGN1 Human Pre-designed siRNA Set A contains three designed siRNAs for JAGN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAK-IN-36 (Compound 12e) is a potent and selective inhibitor of Janus Kinase 1 (JAK1) with a IC50 value of 2.2 nM. JAK-IN-36 can be used in the study of autoimmune diseases[1].
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JAK1 Human Pre-designed siRNA Set A contains three designed siRNAs for JAK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Jak1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Jak1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Jak1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Jak1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAK1/2-IN-1 is a potent JAK1 and JAK2 inhibitor with IC50 values of 0.4 nM and 8.1 nM, respectively. JAK1/2-IN-1 also inhibits IL-4 and IL-13 with IC50s of 136.5 nM and 19.1 nM, respectively (WO2023244775A1; Example 33a)[1].
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MedChem Express
JAK2 Human Pre-designed siRNA Set A contains three designed siRNAs for JAK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Jak2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Jak2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Jak2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Jak2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAK3 covalent inhibitor-2 (compound J1b) is a selective, orally potent JAK3 inhibitor (IC50=7.2 nM) with low toxicity, anti-inflammatory activity and good bioavailability[1].
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JAK3 Human Pre-designed siRNA Set A contains three designed siRNAs for JAK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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MedChem Express
Jak3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Jak3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Jak3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Jak3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAKMIP1 Human Pre-designed siRNA Set A contains three designed siRNAs for JAKMIP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAKMIP2 Human Pre-designed siRNA Set A contains three designed siRNAs for JAKMIP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAKMIP3 Human Pre-designed siRNA Set A contains three designed siRNAs for JAKMIP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAM2 Human Pre-designed siRNA Set A contains three designed siRNAs for JAM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAM3 Human Pre-designed siRNA Set A contains three designed siRNAs for JAM3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAML Human Pre-designed siRNA Set A contains three designed siRNAs for JAML gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JARID2 Human Pre-designed siRNA Set A contains three designed siRNAs for JARID2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JAZF1 Human Pre-designed siRNA Set A contains three designed siRNAs for JAZF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JBC117 is a novel anticancer lead compound targeting Pygo2 PHD. JBC117 can effectively antagonize the cell effect of β-catenin-dependent activity and inhibit the migration and invasion of cancer cells. JBC117 can induce apoptosis[1].
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JBP485 (cyclo-trans-4-L-hydroxyprolyl-L-serine) is a dipeptide with anti-hepatotoxic and wound healing properties. JBP485 can be used for research of various kinds of corneal epithelial diseases[1].
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JCAD Human Pre-designed siRNA Set A contains three designed siRNAs for JCAD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JCHAIN Human Pre-designed siRNA Set A contains three designed siRNAs for JCHAIN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JD-02 is a novel Hsp90 inhibitor. JD-02 can induce autophagy and apoptosis. JD-02 increses the level of reactive oxygen species[1].
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JDP2 Human Pre-designed siRNA Set A contains three designed siRNAs for JDP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JGB-1-155 is a positive allosteric modulators (N-PAMs), which enhances the activity of nicotinamide phosphoribosyltransferase NAMPT with EC50 of 3.29 μM. JGB-1-155 counteracts the oxidative stress, through upregulating the NAD+ in THP-1 human monocytes. JGB-1-155 attenuates TNFα-induced ROS in HT-22 cells [1].
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JHY Human Pre-designed siRNA Set A contains three designed siRNAs for JHY gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JJC8-088 is a potent inhibitor of DAT. JJC8-088 is a novel Modafinil-derived ligands. JJC8-088 can be used to study psychostimulant use disorders[1].
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JKAMP Human Pre-designed siRNA Set A contains three designed siRNAs for JKAMP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JMJD1C Human Pre-designed siRNA Set A contains three designed siRNAs for JMJD1C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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JMJD1C-IN-1 (compound 193D7) is an inhibitor of JMJD1C with oral activity. JMJD1C-IN-1 targets tumor Treg cells without affecting systemic immune homeostasis[1].
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JMJD1C-IN-1 (compound 193D7) is an inhibitor of JMJD1C with oral activity. JMJD1C-IN-1 targets tumor Treg cells without affecting systemic immune homeostasis[1].
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JMJD1C-IN-1 (compound 193D7) is an inhibitor of JMJD1C with oral activity. JMJD1C-IN-1 targets tumor Treg cells without affecting systemic immune homeostasis[1].
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JMJD1C-IN-1 (compound 193D7) is an inhibitor of JMJD1C with oral activity. JMJD1C-IN-1 targets tumor Treg cells without affecting systemic immune homeostasis[1].
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JMJD1C-IN-1 (compound 193D7) is an inhibitor of JMJD1C with oral activity. JMJD1C-IN-1 targets tumor Treg cells without affecting systemic immune homeostasis[1].
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JMJD4 Human Pre-designed siRNA Set A contains three designed siRNAs for JMJD4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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