MedChem Express
AChE-IN-59 (compounds 3b) is an AChE inhibitor, with an IC50 value of 0.05 μM. AChE-IN-59 can inhibit the aggregation of Aβ1-42, protect nerve cells and penetrate the blood-brain barrier well. AChE-IN-59 can be used for the research of Alzheimer’s disease (AD)[1].
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AChE-IN-60 (compound 6k) is a potant acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitor with IC50s of 27 nM and 43 nM, respectively. AChE-IN-60 also inhibits monoamine oxidase (MAO)-A and MAO-B with IC50s of 353 nM and 716 nM, respectively[1].
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AChE-IN-62 (Compound 1) is an effective mixed and selective acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.421 μM. AChE-IN-62 exhibits excellent blood-brain barrier permeability and neuroprotective effects. Additionally, AChE-IN-62 can inhibit the aggregation of Aβ1?42 with an IC50 value of 44.64 μM. AChE-IN-62 is also an effective multi-target-directed ligand (MTDL) that can be utilized […]
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AChE-IN-63 (Compound 5AD) is a selective inhibitor of hAChE (IC50=0.103 μM). AChE-IN-63 also inhibits hBChE and hBACE-1 (IC50= 10 μM (hBChE); 1.342 μM (hBACE-1)). AChE-IN-63 inhibits Aβ aggregation, preventing the formation and deposition of Aβ1-42. AChE-IN-63 can effectively penetrate the blood-brain barrier and is orally effective. It is primarily used in Alzheimer’s disease research[1].
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AChE/Aβ-IN-5 (compound AV-2) is a bifunctional inhibitor that targets AChE and auto-induced Aβ (Amyloid-β) aggregation. AChE/Aβ-IN-5 can significantly improve scopolamine- and Aβ-induced cognitive impairment in mice[1].
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AChE/BChE-IN-18 (Compound 4g) is a dual inhibitor of AChE/BChE , with a IC50 value of 0.315 μM for AchE. AChE/BChE-IN-18 is also a CB2R antagonist with a Ki value of 31 nM. AChE/BChE-IN-18 has neuroprotective activity[1].
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AChE/BChE-IN-19 (Compound 12) is a nicotinic hydrazide derivative. AChE/BChE-IN-19 (Compound 12) is a inhibitor of AChE (IC50 = 21.45 nM) and BChE (IC50 =18.42 nM). AChE/BChE-IN-19 (Compound 12) can be used in Alzheimer’s disease research[1].
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ACHP (compound 4j) is a selective and orally active IκB kinase inhibitor with IC50 values of 8.5 nM and 250 nM for IKKβ and IKKα, respectively. ACHP can effectively inhibit the STAT3 signaling pathway and induce cancer cell cycle arrest and apoptosis. ACHP shows anti-inflammatory activity in a mouse ear edema model. ACHP can be […]
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Acid black 24 is a black agent whose staining effect is effectively removed by nanoscale zero-valent iron (NZVI) particles. The maximum unit removal capacity is 609.4 mg of dye per gram of NZVI.
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Acid blue 113 is an azo dye whose staining effect is effectively removed by nanoscale zero-valent iron (NZVI) particles.
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Acid blue 260 is an azo dye whose staining effect is effectively removed by multi-walled carbon nanotubes (MWCNTs). At 298 K, the adsorption capacity of MWCNT is 233.34 mg/g; and increases with the increase of dye concentration and temperature.
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Acid green 12 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are […]
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Acid red 119 is an acid red dye that can be removed from aqueous solutions when polyaluminum chloride (PAC) and polyaluminum chloride sludge (PACS) are used as coagulants.
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Acid red 260 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are […]
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Acid red 266 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are […]
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ACIN1 Human Pre-designed siRNA Set A contains three designed siRNAs for ACIN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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ACKR1 Human Pre-designed siRNA Set A contains three designed siRNAs for ACKR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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ACKR2 Human Pre-designed siRNA Set A contains three designed siRNAs for ACKR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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ACKR3 Human Pre-designed siRNA Set A contains three designed siRNAs for ACKR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Ackr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ackr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Ackr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ackr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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ACKR4 Human Pre-designed siRNA Set A contains three designed siRNAs for ACKR4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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ACLY Human Pre-designed siRNA Set A contains three designed siRNAs for ACLY gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Acly Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acly gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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