MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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DNMT/HDAC-IN-1 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

DNMT/HDAC-IN-1 (Compund 15a) is a dual DNMT and HDAC inhibitor with IC50 values for HDAC1 and HDAC6 are 56.84 nM and 17.39 nM respectively. DNMT/HDAC-IN-1 can induce apoptosis and be used in tumor research.

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DNMT3A-IN-2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

DNMT3A-IN-2 (compound 1a) is a hydrophthalazinone-based inhibitor of DNA methyltransferase 3A (DNMT3A) (IC50: 14 μM) against S-adenosylmethionine (SAM) has a Ki of 9.16-18.85 μM.[14][1].

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DNMT3A-IN-3 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

DNMT3A-IN-3 is an allosteric DNA methyltransferase 3A (DNMT3A) inhibitor. DNMT3A-IN-3 binds and disrupt protein-protein interactions (PPIs) at the DNMT3A tetramer interface[1].

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DNP-INT | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

DNP-INT is a potent photosynthetic electron transport chain (PETC) inhibitor. DNP-INT competently inhibits the oxidation of plastid quinoline by binding to the Q0 site of Cyt-b6f (Kd=1.4 nM), thereby inhibiting electron transfer in plants[1].

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DO2A | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

DO2Ais a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO2A can be used for conjugation of peptides and radionuclides.

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DO2A-tert-butyl ester | MedChemExpress (MCE) 10 mg  | ≥98.0%

MedChem Express

DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers[1].

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DO2A-tert-butyl ester | MedChemExpress (MCE) 25 mg  | ≥98.0%

MedChem Express

DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers[1].

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DO2A-tert-butyl ester | MedChemExpress (MCE) 50 mg  | ≥98.0%

MedChem Express

DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers[1].

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DO2A-tert-butyl ester | MedChemExpress (MCE) 100 mg  | ≥98.0%

MedChem Express

DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers[1].

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DO3A trisodium | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

DO3A (trisodium)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO3A (trisodium) can be used for conjugation of peptides and radionuclides.

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Docetaxel (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Docetaxel (Standard) is the analytical standard of Docetaxel. This product is intended for research and analytical applications. Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity[1][3].

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