MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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SB-505124 (hydrochloride) 10mg  | ≥98%

MedChem Express

SB-505124 hydrochloride is a selective inhibitor of TGFβR with IC50 of 129 nM and 47 nM for ALK4, ALK5, respectively, and it does not inhibits ALK1, 2, 3, or 6 but ALK7. IC50 & Target: IC50: 129 nM (ALK4), 47 nM (ALK5) In Vitro: SB-505124 demonstrates no toxicity to renal epithelial A498 cells at concentrations up to 100 μM […]

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SB-505124 hydrochloride 10 mg  | Purity Not Available

MedChem Express

SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.

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SB-505124 hydrochloride 50 mg  | Purity Not Available

MedChem Express

SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.

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SB-568849 1mg  | ≥98%

MedChem Express

SB-568849 is a melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pKi of 7.7. IC50 & Target: MCH R1 receptor[1] In Vitro: SB-568849 is a selective SLC-1 antagonist with a pKi of 7.7 as determined in radioligand binding displacement assays; coincubation of tissue with 1 μM SB-568849 for 45 min completely inhibits the MCH […]

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SB-568849 5mg  | ≥98%

MedChem Express

SB-568849 is a melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pKi of 7.7. IC50 & Target: MCH R1 receptor[1] In Vitro: SB-568849 is a selective SLC-1 antagonist with a pKi of 7.7 as determined in radioligand binding displacement assays; coincubation of tissue with 1 μM SB-568849 for 45 min completely inhibits the MCH […]

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SB-568849 10mg  | ≥98%

MedChem Express

SB-568849 is a melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pKi of 7.7. IC50 & Target: MCH R1 receptor[1] In Vitro: SB-568849 is a selective SLC-1 antagonist with a pKi of 7.7 as determined in radioligand binding displacement assays; coincubation of tissue with 1 μM SB-568849 for 45 min completely inhibits the MCH […]

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SB-568849 1 mg  | Purity Not Available

MedChem Express

SB-568849 is a melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pKi of 7.7.

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SB-568849 5 mg  | Purity Not Available

MedChem Express

SB-568849 is a melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pKi of 7.7.

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SB-568849 10 mg  | Purity Not Available

MedChem Express

SB-568849 is a melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pKi of 7.7.

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SB-590885 10 mM * 1 mL  | 99.03%

MedChem Express

SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases.

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SB-590885 10 mg  | 99.03%

MedChem Express

SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases.

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SB-590885 50 mg  | 99.03%

MedChem Express

SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases.

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SB-590885 100 mg  | 99.03%

MedChem Express

SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases.

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SB-590885 50mg  | ≥98%

MedChem Express

SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases. IC50 & Target: IC50: 0.16 nM (B-Raf) In Vitro: SB-590885 displays significant selectivity for B-Raf over c-Raf with Ki of 0.16 nM over 1.72 nM. SB-590885 is a more potent inhibitor than the previously […]

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SB-590885 100mg  | ≥98%

MedChem Express

SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases. IC50 & Target: IC50: 0.16 nM (B-Raf) In Vitro: SB-590885 displays significant selectivity for B-Raf over c-Raf with Ki of 0.16 nM over 1.72 nM. SB-590885 is a more potent inhibitor than the previously […]

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SB-590885 10mg  | ≥98%

MedChem Express

SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases. IC50 & Target: IC50: 0.16 nM (B-Raf) In Vitro: SB-590885 displays significant selectivity for B-Raf over c-Raf with Ki of 0.16 nM over 1.72 nM. SB-590885 is a more potent inhibitor than the previously […]

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SB-590885 10mM/1mL  | ≥98%

MedChem Express

SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases. IC50 & Target: IC50: 0.16 nM (B-Raf) In Vitro: SB-590885 displays significant selectivity for B-Raf over c-Raf with Ki of 0.16 nM over 1.72 nM. SB-590885 is a more potent inhibitor than the previously […]

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SB-616234A 1 mg  | Purity Not Available

MedChem Express

SB-616234A is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity.

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SB-616234A 5 mg  | Purity Not Available

MedChem Express

SB-616234A is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity.

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SB-616234A 10 mg  | Purity Not Available

MedChem Express

SB-616234A is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity.

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SB-616234A 1mg  | ≥98%

MedChem Express

SB-616234A is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity. In Vitro: SB-616234A possesses high affinity for human 5-HT1B receptors stably expressed in Chinese hamster ovary (CHO) cells (pKi 8.3 ± 0.2), and is over 100-fold selective for a range of molecular targets except h5-HT1D receptors (pKi 6.6 ± 0.1). […]

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SB-616234A 5mg  | ≥98%

MedChem Express

SB-616234A is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity. In Vitro: SB-616234A possesses high affinity for human 5-HT1B receptors stably expressed in Chinese hamster ovary (CHO) cells (pKi 8.3 ± 0.2), and is over 100-fold selective for a range of molecular targets except h5-HT1D receptors (pKi 6.6 ± 0.1). […]

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SB-616234A 10mg  | ≥98%

MedChem Express

SB-616234A is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity. In Vitro: SB-616234A possesses high affinity for human 5-HT1B receptors stably expressed in Chinese hamster ovary (CHO) cells (pKi 8.3 ± 0.2), and is over 100-fold selective for a range of molecular targets except h5-HT1D receptors (pKi 6.6 ± 0.1). […]

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SB-649868 10mM/1mL  | ≥98%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively). IC50 & Target: pKi: 9.4 (OX1), 9.5 (OX2)[1] In Vitro: SB-649868 is identified as one the most in vitro potent dual OX1 and OX2 receptor antagonist known at that […]

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SB-649868 25mg  | ≥98%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively). IC50 & Target: pKi: 9.4 (OX1), 9.5 (OX2)[1] In Vitro: SB-649868 is identified as one the most in vitro potent dual OX1 and OX2 receptor antagonist known at that […]

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SB-649868 50mg  | ≥98%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively). IC50 & Target: pKi: 9.4 (OX1), 9.5 (OX2)[1] In Vitro: SB-649868 is identified as one the most in vitro potent dual OX1 and OX2 receptor antagonist known at that […]

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SB-649868 100mg  | ≥98%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively). IC50 & Target: pKi: 9.4 (OX1), 9.5 (OX2)[1] In Vitro: SB-649868 is identified as one the most in vitro potent dual OX1 and OX2 receptor antagonist known at that […]

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SB-649868 1mg  | ≥98%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively). IC50 & Target: pKi: 9.4 (OX1), 9.5 (OX2)[1] In Vitro: SB-649868 is identified as one the most in vitro potent dual OX1 and OX2 receptor antagonist known at that […]

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SB-649868 5mg  | ≥98%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively). IC50 & Target: pKi: 9.4 (OX1), 9.5 (OX2)[1] In Vitro: SB-649868 is identified as one the most in vitro potent dual OX1 and OX2 receptor antagonist known at that […]

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SB-649868 10mg  | ≥98%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively). IC50 & Target: pKi: 9.4 (OX1), 9.5 (OX2)[1] In Vitro: SB-649868 is identified as one the most in vitro potent dual OX1 and OX2 receptor antagonist known at that […]

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SB-649868 10 mM * 1 mL  | 99.88%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

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SB-649868 1 mg  | 99.88%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

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SB-649868 5 mg  | 99.88%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

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SB-649868 10 mg  | 99.88%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

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SB-649868 25 mg  | 99.88%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

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SB-649868 50 mg  | 99.88%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

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SB-649868 100 mg  | 99.88%

MedChem Express

SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

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SB-674042 10mM/1mL  | ≥98%

MedChem Express

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors. IC50 value: 3.76 nM (Kd) Target: OX1 receptor SB-674042 has no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca2+ mobilization in CHO-DG44 cells stably transfected with the OX1 […]

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SB-674042 5mg  | ≥98%

MedChem Express

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors. IC50 value: 3.76 nM (Kd) Target: OX1 receptor SB-674042 has no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca2+ mobilization in CHO-DG44 cells stably transfected with the OX1 […]

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SB-674042 10mg  | ≥98%

MedChem Express

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors. IC50 value: 3.76 nM (Kd) Target: OX1 receptor SB-674042 has no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca2+ mobilization in CHO-DG44 cells stably transfected with the OX1 […]

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SB-674042 10 mM * 1 mL  | 99.7%

MedChem Express

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

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SB-674042 5 mg  | 99.7%

MedChem Express

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

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SB-674042 10 mg  | 99.7%

MedChem Express

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

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SB-681323 10mM/1mL  | ≥98%

MedChem Express

SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. In Vitro: SB-681323 potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression[1].

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SB-681323 20mg  | ≥98%

MedChem Express

SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. In Vitro: SB-681323 potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression[1].

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SB-681323 1mg  | ≥98%

MedChem Express

SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. In Vitro: SB-681323 potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression[1].

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SB-681323 5mg  | ≥98%

MedChem Express

SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. In Vitro: SB-681323 potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression[1].

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SB-681323 10mg  | ≥98%

MedChem Express

SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. In Vitro: SB-681323 potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression[1].

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SB-705498 10 mM * 1 mL  | 99.61%

MedChem Express

SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.1.

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SB-705498 5 mg  | 99.61%

MedChem Express

SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.1.

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