Creative Peptides
Creative Peptides
Substance P is a neuropeptide, acting as a neurotransmitter and as a neuromodulator.The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
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Substance P (SP) is an endogenous tachykinin neuropeptide that is involved in inflammatory, pain, and stress signaling; it exhibits neuroprotective, cognition-enhancing, and gastrointestinal motility modulating activities. SP is the natural ligand for the neurokinin-1 (NK1) receptor.
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Substance P (1-7)(TFA) is a fragment of the neuropeptide, substance P (SP). Substance P (1-7)(TFA) gives depressor and bradycardic effects when applied to the nucleus tractus solitarius.
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Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.
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Substance P (7-11) is a C-terminal fragment of Substance P which can cause an increase in the intracellular calcium concentration.
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The undecapeptide substance P has a number of peripheral actions which include contraction of smooth muscle, reduction of blood pressure and stimulation of secretory tissues. Substance P also occurs in neurones in the central nervous system. It is of particular interest as a possible neurotransmitter or neuromodulator, released by primary sensory neurones.
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Creative Peptides
Creative Peptides
Subtilosin A is 35-amino acid cyclic peptide with three cysteine bridges from Bacillus subtilis 168; It has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium
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