QL9
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| >95%
Creative Peptides
Creative Peptides
The CPK R – PE Labeling Kit is ideally suited to label antibodies. In practical applications, the sensitivity of R-PE conjugates is usually 5 to 10 times greater than those of the corresponding fluorescein conjugates. R-PE, a fluorescent protein from phycobiliprotein family, has broad absorption bands with peaks at 565 nm (eM =1.96 X 106 […]
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R 715
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| >98%
Creative Peptides
Potent and selective antagonist of bradykinin b1 receptor (pa2 = 8.49), which displays no activity at b2 receptors, and reduces mechanical hypernociception in a mouse model of neuropathic pain.
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R 892
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| >98%
Creative Peptides
Potent and selective bradykinin B1 receptor antagonist (ID50 values are 2.8 and > 600 nM at B1 and B2 receptors respectively), which shows no intrinsic agonist activity and is resistant to aminopeptidase and kininase II (ACE) cleavage. Displays hypertensive activity in vivo.
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R18
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| >98%
Creative Peptides
An antagonist of 14.3.3 proteins (KD ≈80 nM) that induces apoptosis. Competitively inhibits 14-3-3-ligand interactions without requiring phosphorylation, thereby blocks the ability of 14-3-3 binding to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S.
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Creative Peptides
R8-T198wt, derived from p27Kip1, is cell-permeable peptide inhibitor of Pim-1 kinase. It Inhibits Pim-1 phosphorylation of p27Kip1 and Bad, and induces cell cycle arrest (at G1) and apoptosis in DU145 prostate cancer cells. It is primarily used for Cancer applications.
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R9-TAT
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| >95%
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R9-Tat is the arginine-substituted analog for the HIV Tat protein (48-60). Similar to Tat (48-60), R9-Tat is internalized by macrophages and translocated to the nucleus and cytoplasm. Additionally, R9-Tat is efficient in intracellular protein delivery, serving as a protein carrier for Carbonic anhydrase into the cell.
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Creative Peptides
Rabies Virus Glycoprotein is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells.
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Creative Peptides
Creative Peptides
A peptide containing residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1, which is specific inhibitor of Rac1-GEF interaction.
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RADA 16
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| >95%
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RADA-16 peptides form highly hydrated hydrogels, allowing for the entrapment and gradual release of small molecules and proteins.
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Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF-κB activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.
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Creative Peptides
Ramoplanin is used as a treatment for multiple antibiotic-resistant Clostridium difficile infection of the gastrointestinal tract.
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Creative Peptides
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D.
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