Creative Peptides
pJAK2(1001-1013) is a small peptide antagonist of SOCS-1 that had both an antiviral effect in keratinocytes against HSV-1 as well as a synergistic effect on IFNγ induction of an antiviral state.
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Creative Peptides
PKA inhibitor fragment (6-22) amide is the shortest synthetic PKI peptide, and acts as a potent protein kinase A (PKA) inhibitor.
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Creative Peptides
PKC (19-36), corresponding to PKC pseudosubstrate regulatory sequence, is a potent and selective protein kinase C (PKC) inhibitor.
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Creative Peptides
Selective cell-permeable PKC inhibitor peptide. Consists of amino acids 19 – 31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide.
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Creative Peptides
Creative Peptides
PKI (14-22) amide (myristoylated) is cell-permeable protein kinase A inhibitor. The non-myristoylated type of this peptide is a highly specific inhibitor of cAMP-dependent protein kinase (PKA), N-terminus is myristoylated to increase cell membrane permeability. It is usually used to study PKA in cellular systems in-vitro.
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Creative Peptides
This FRET substrate peptide for Plasmepsin V (PMV) is derived from the conserved Plasmodium Export Element (PEXEL) motif of Histidine-Rich Protein II (HRPII). PMV is an ER aspartic protease that recognizes and cleaves the RXL sequence within the PEXEL motif of proteins exported by human malaria parasite Plasmodium falciparum, allowing them to translocate into host […]
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The P. falciparum circumsporozoite protein (PfCSP) is the most abundant antigen expressed on the surface of P. falciparum sporozoites. This pre-erythrocytic antigen contains a stretch of 6 highly conserved, immunodominant tetrapeptide repeats (NANP) in the middle, while its N- and C-terminal regions contain two crucial protective regions termed RI and RII-plus, respectively. Both play key […]
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Creative Peptides
Platelet Factor 4 (58-70), human, a peptide based on the amino acid sequence corresponding to residues 58-70 of platelet factor-4 (PF-4), contains the major heparin-binding domain, which is not sufficient for full antiangiogenic activity.
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Creative Peptides
Plecanatide is a minimally absorbed agonist of guanylate cyclase C receptors in the intestine and is used for treatment of chronic constipation and irritable bowel syndrome. Plecanatide has not been linked to serum enzyme elevations during treatment or to episodes of clinically apparent liver injury.
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