Creative Peptides
PD-1/PD-L1 Inhibitor is a macrocyclic inhibitor of PD-1/PD-L1 interaction with an IC50 of 5.6 nM. In vitro ab231310 is capable of inhibiting the interaction of PD-L1 with PD-1 and with CD80. It has highly efficacious binding to PD-L1 and promotes enhanced T cell functional activity.
More Information
Supplier Page
Creative Peptides
740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone.
More Information
Supplier Page
PDKtide
Inquiry
| >95%
Creative Peptides
Creative Peptides
A cyclic peptide that disrupts interaction between GluK2 (formally GluR6) and postsynaptic density protein 95 (PSD-95) through competing with the C terminal of GluK2 to bind the PDZ1 domain of PSD-95. It inhibits clustering of kainate receptors.
More Information
Supplier Page
PE22-28
Inquiry
| >95%
Creative Peptides
PEG-MGF
Inquiry
| >95%
Creative Peptides
PEG-MGF is a derived form of the IGF-1 (insulin-like growth factor-1), which stimulates myoblasts division and allows for muscle fibers to fuse and mature. This is a process necessary for the growth of adult muscle. The distinction between IGF-1 and MGF is that MGF stimulates myoblasts division through the stimulation of different receptors. Research has […]
More Information
Supplier Page
Creative Peptides
Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. Peginesatide consists of two 21-amino acid […]
More Information
Supplier Page
Pen2W2F
Inquiry
| >95%
Creative Peptides
Creative Peptides
Penetratin, the first 16 amino acids of which are derived from the third helix of the Antennapedia protein homeodomain, is known as a protein transduction domain (PTD). Penetratin linked to a phosphodiester oligonucleotide is capable of permeating through neuronal cell membranes and down-regulating genes. It contains a nuclear localization sequence and facilitates internalization of cargo […]
More Information
Supplier Page
Creative Peptides
Penetratin-Arg , derived from the 3rd helix of Drosophila Antennapedia homeodomain protein, can permeate cell membrane at low micromolar concentration without significantly affecting membrane.It contains a nuclear localization sequence and facilitates internalization of cargo into living cells.
More Information
Supplier Page
Creative Peptides
Pentadecanedioic acid is a dicarboxylic acid with the molecular formula C15H26O4. It is a white solid with a melting point of about 140°C. It is insoluble in water but soluble in organic solvents. It is used in the production of polyesters, plasticizers, and lubricants.
More Information
Supplier Page