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This is a cell-penetrating peptide (CPP) that is derived from the human immunoglobulin heavy chain sequence. It can permeate cell membrane at low micromolar concentration without significantly affecting cell membrane. CPP can be conjugated with large molecules and used as a drug delivery vehicle.
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P11
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| >98%
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P11 is potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). It can blocks proliferation and induces apoptosis in HUVECs. It exhibits antiangiogenic property.
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Creative Peptides
This peptide is derived from bovine peripheral myelin P2 protein amino acid residues 53-78. It is neuritogenic, inducing experimental autoimmune neuritis (EAN) in Lewis rats.
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Creative Peptides
This peptide sequence is found in residues 14 to 30 of P22 N. P22 N is a transcriptional antiterminator that binds to N-utilization (NUT) sites on viral transcripts. P22 N modifies RNA polymerase activity by creating a termination-resistant form of the RNA polymerase complex that is able to continue transcribing the viral transcript.
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p2Ca
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| >95%
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p2Ca, an 8-mer peptide, is a ligand that is naturally processed and presented to the Ld-alloreactive T cell clone, 2C.
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Creative Peptides
p5 Ligand for Dnak and DnaJ is a nonapeptide, which corresponds to the main binding site for the 23-residue part of the presequence of mitochondrial aspartate aminotransferase. p5 Ligand for Dnak and DnaJ is a high-affinity ligand for DnaK and DnaJ.
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Creative Peptides
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Creative Peptides
PAC-113
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| >95%
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PAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva.
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Creative Peptides
PACAP (1-27), human, ovine, rat, the N-terminal fragment of PACAP-38, is a potent PACAP receptor antagonist with IC50s of 3, 2, and 5 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2.
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Creative Peptides
PACAP (1-38), human, ovine, rat is a neuropeptide with 38 amino acid residues. PACAP (1-38) binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively.
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PACAP (1-38), human, ovine, rat TFA is a neuropeptide with 38 amino acid residues. PACAP (1-38) binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively.
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PACAP (6-38), human, ovine, rat is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively.
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Creative Peptides
PACAP (6-38), human, ovine, rat TFA is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively.
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PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP is a potent activator of cAMP formation.
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Creative Peptides
PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP is a potent activator of cAMP formation.
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