Creative Peptides
LPYFD-NH2 is a neuroprotective peptide that binds to amyloid beta (Aβ) and protects neurons against toxic effects of Aβ (1-42) in vitro and in vivo.
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Creative Peptides
LSKL, Inhibitor of Thrombospondin (TSP-1) is a peptide derived from the latency-associated peptide, inhibits thrombospondin (TSP-1) activation of TGF-β and prevents the progression of hepatic damage and fibrosis.
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LTX-315
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Creative Peptides
LTX-315 is an oncolytic peptide with potent anticancer activity; inhibits MRC-5, A20 and AT84 with IC50s of 34.3, 8.3 and 11 μM, respectively.
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Creative Peptides
Luciferase from Vibrio fischeri has also been used in a study to investigate the sensitivity of dark mutants of various strains of luminescent bacteria to reactive oxygen species.
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Creative Peptides
Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles.
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Creative Peptides
Lucinactant contains the peptide sinapultide (KL4 acetate, KLLLLKLLLLKLLLLKLLLLK), dipalmitoylphosphatidylcholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol (as the sodium salt), and palmitic acid.
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Creative Peptides
Luteinizing hormone-releasing hormone (LHRH or Gonadotropin-releasing hormone [GnRH]) is an endogenous peptide hormone that binds the GnRH receptor, stimulating the secretion of reproductive hormones (such as luteinizing hormone [LH] and follicle-stimulating hormone [FSH]) from the pituitary gland. Analogs of GnRH are clinically used to treat hormone-dependent diseases such as prostate and breast cancer, hyperplasia, and […]
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Creative Peptides
Lutetium Lu 177 Dotatate is a radioconjugate consisting of the tyrosine-containing somatostatin analog Tyr3-octreotate (TATE) conjugated with the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and radiolabeled with the beta-emitting radioisotope lutetium Lu 177, with potential imaging and antineoplastic activities. Lutetium Lu 177 dotatate binds to somatostatin receptors (SSTRs), with high affinity to type 2 […]
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