Creative Peptides
HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis.
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Creative Peptides
HiLyte Fluor 488 has excitation and emission spectrum peak wavelengths of approximately 497 nm/525 nm, giving it a green color. The spectrum of HiLyte Fluor488 is similar to fluorescein (FITC), resulting in an optimal match to filters designed for fluorescein. Protein conjugates prepared with HiLyte Fluor 488 dyes are far more superior compared to conjugates […]
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Creative Peptides
HiLyte Fluor 555 acid, SE has excitation and emission spectrum peak wavelengths of approximately 553 nm/ 568 nm, giving it an orange color. HiLyte Fluor 555 acid, SE is an excellent amine-reactive fluorescent labeling dye that generates the protein conjugates that are only slightly red-shifted compared to those of Cy 3 dyes, resulting in an […]
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Creative Peptides
HiLyte Fluor 647 acid, SE is an excellent fluorescent labeling dye that generates the protein conjugates that are slightly red-shifted compared to those of Cy 5 dyes, resulting in an optimal match to filters designed for Cy 5 dyes. Compare to Cy 5, HiLyte Fluor 647 have very little change in absorption or fluorescence spectra […]
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Creative Peptides
HiLyte Fluor 750 acid, SE is the longest-wavelength amine-reactive HiLyte Fluor dye currently available. It has excitation and emission spectrum peak wavelengths of approximately 754 nm/ 778 nm. Its fluorescence emission maximum at 778 nm is well separated from commonly used far-red fluorophores such as HiLyte Fluor 647, HiLyte Fluor 680 or allophycocyanin (APC), facilitating […]
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Creative Peptides
His-Ala
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Creative Peptides
His-Ala is a dipeptide formed from L-histidine and L-alanine residues. It has a role as a metabolite. It is a tautomer of a His-Ala zwitterion.
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His-Pro
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Creative Peptides
Creative Peptides
Creative Peptides
Histatin 5 inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
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Creative Peptides
Histatin 5 has been shown to inhibit clostripain and a tyrpsin-like protease poduced by Bacteroides gingivalis. Â Other proteases have not been inhibited by histain 5. Â Histatin 5 has been suggested as a preventive against peridontalgum disease.
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Creative Peptides
Creative Peptides
This novel fluorogenic substrate of HDACs was synthesized with an epsilon-acetylated lysyl moiety and an adjacent MCA moiety at the C-terminus of the peptide chain. The assay utilizing this substrate provides a good tool to characterize the HDAC activity. HDACs are important enzymes for the transcriptional regulation of gene expression.
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Creative Peptides
Histone H1-derived peptide, phosphorylated by protein kinase A, is a substrate for CDK2 and CDK5 (cyclin dependent kinase 5) and PKA.
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