Creative Diagnostics
Milk is one of the first food components introduced into the diet and therefore represents one of the most important food allergen sources in terms of frequency and severity of allergic manifestations. The symptoms of cow’s milk allergy are due to IgE-mediated activation of mast cells and basophils as well as to activation of allergen-specific […]
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Milk is one of the first food components introduced into the diet and therefore represents one of the most important food allergen sources in terms of frequency and severity of allergic manifestations. The symptoms of cow’s milk allergy are due to IgE-mediated activation of mast cells and basophils as well as to activation of allergen-specific […]
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Creative Diagnostics
Creative Diagnostics
Fel d 1 is a secretoglobin protein that, in cats, is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes. Among cats, Fel d 1 is produced largely in their saliva and by the sebaceous glands located in their skin. It is the primary allergen present on cats and […]
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IgE-mediated hypersensitive reactions to ingestion of shellfish are among the most serious forms of food allergies.Cha f 1 is a 34-kd recombinant protein reactive to the IgE antibodies from patients with crab allergies.
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Che a 1, a relevant allergen from chenopod pollen, is structurally related to the Ole e 1-like protein family, but exhibits significant differences on its polypeptide sequence that could explain its different antigenic behavior and limited cross-reactivity.
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Egg allergy accounts for one of the most prevalent food hypersensitivities in industrialized countries. The majority of the relevant egg allergens have been identified in the egg white: ovomucoid (Gal d 1), a Kazal-type serine protease inhibitor; ovoalbumin (Gal d 2), a serine protease inhibitor; ovotransferrin (Gal d 3); and the egg lysozyme (Gal d […]
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Creative Diagnostics
Egg allergy accounts for one of the most prevalent food hypersensitivities in industrialized countries. The majority of the relevant egg allergens have been identified in the egg white: ovomucoid (Gal d 1), a Kazal-type serine protease inhibitor; ovoalbumin (Gal d 2), a serine protease inhibitor; ovotransferrin (Gal d 3); and the egg lysozyme (Gal d […]
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Creative Diagnostics
Egg allergy accounts for one of the most prevalent food hypersensitivities in industrialized countries. The majority of the relevant egg allergens have been identified in the egg white: ovomucoid (Gal d 1), a Kazal-type serine protease inhibitor; ovoalbumin (Gal d 2), a serine protease inhibitor; ovotransferrin (Gal d 3); and the egg lysozyme (Gal d […]
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Creative Diagnostics
Egg allergy accounts for one of the most prevalent food hypersensitivities in industrialized countries. The majority of the relevant egg allergens have been identified in the egg white: ovomucoid (Gal d 1), a Kazal-type serine protease inhibitor; ovoalbumin (Gal d 2), a serine protease inhibitor; ovotransferrin (Gal d 3); and the egg lysozyme (Gal d […]
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Creative Diagnostics
Egg allergy accounts for one of the most prevalent food hypersensitivities in industrialized countries. The majority of the relevant egg allergens have been identified in the egg white: ovomucoid (Gal d 1), a Kazal-type serine protease inhibitor; ovoalbumin (Gal d 2), a serine protease inhibitor; ovotransferrin (Gal d 3); and the egg lysozyme (Gal d […]
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Creative Diagnostics
Egg allergy accounts for one of the most prevalent food hypersensitivities in industrialized countries. The majority of the relevant egg allergens have been identified in the egg white: ovomucoid (Gal d 1), a Kazal-type serine protease inhibitor; ovoalbumin (Gal d 2), a serine protease inhibitor; ovotransferrin (Gal d 3); and the egg lysozyme (Gal d […]
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Creative Diagnostics
Major pollen allergen Cor a 1 (Cor a 1.0103) causes an allergic reaction in human. The Cor a 1 isoforms exhibit different antigenic and allergenic properties.
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Cor a 1.0401 represents the major hazelnut allergen from Corylus avellana. This pathogenesis-related protein, PR-10, belongs to the family of Bet v1 homologues and is closely related to the major hazel pollen allergen Cor a 1.0103.
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Seed storage proteins have been identified as major allergens in several other tree nuts and peanut. 2S albumin Cor a 14.0101 is an abundant seed storage protein in hazelnut. Sensitization to Cor a 14.0101 has been shown to be a risk marker for severe allergic reactions, especially in children.
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Nonspecific lipid transfer proteins (nsLTPs) are expressed throughout the plant tissues. They are characterized by a typical cysteine pattern forming disulfide bonds and are known as important allergens in fruits and tree nuts. Sensitization to nsLTP Cor a 8.0101 has been shown to be clearly more frequent among patients with hazelnut allergy in the Mediterranean […]
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DERP2 is a cause of an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis. This protein and and Dermatophagoides farinae (Der f) are the major source of allergens for patients allergic to house dust mites (HDMs).
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DERP2 is a cause of an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis. This protein and and Dermatophagoides farinae (Der f) are the major source of allergens for patients allergic to house dust mites (HDMs).
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Der p 23 is a new major allergen of D. pteronyssinus. The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma. Der p 23 may be an essential component for diagnosis and specific immunotherapy of HDM allergy.
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Dust mite allergy, also known as house dust allergy, is a sensitization and allergic reaction to the droppings of house dust mites. The allergy is common and can trigger allergic reactions such as asthma, eczema or itching. It is the manifestation of a parasitosis. The mite’s gut contains potent digestive enzymes (notably peptidase 1) that […]
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The major allergens are proteins found in fecal balls. A half teaspoon of house dust contains about 250,000 fecal pellets, which are of the same size as respirable pollens. The most significant allergens (Der p1 and Der p2) are cysteine proteases.
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Fel d 4 is a lipocalin allergen produced by the cat, which binds IgE at relatively high frequency in cat-sensitive individuals. The allergen provides not only a means for investigating differences in the immune response to lipocalin allergens from that found for other mammalian species but also an important reagent for the diagnosis of cat […]
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