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Imagine the power of people with a common purpose to build relationships that create value for you and your business. This is ChemScene. Every day, our people work with you to ensure you have what you need to achieve your commercial and scientific pursuits. We make sure everything we do honors that relationship starting from our commitment to ensuring that our chemicals are held to the most rigorous quality standards in the world, to the way we engage with our customers and communities to do business responsibly.

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(S)-Thalidomide| ChemScene 25mg  | >98%

ChemScene

(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-enantiomer of Thalidomide. (S)-Thalidomide has immunomodulatory, anti-inflammatory, antiangiogenic and pro-apoptotic effects[2]. (S)-Thalidomide induces teratogenic effects by binding to cereblon (CRBN) .IC50 & Target: ApoptosisIn Vitro: (S)-Thalidomide treatment results in a reduction in cell viability in U266 cells with an IC50 of 362 μM.(S)-Thalidomide treatment increased apoptosis in a dose-dependent manner in […]

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(S)-TXNIP-IN-1| ChemScene 5mg  | >98%

ChemScene

(S)-TXNIP-IN-1 is the less active S-enantiomer of TXNIP-IN-1 (HY-115688). TXNIP-IN-1 is a TXNIP-TRX complex inhibitor which can be used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease

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(S)-UFR2709 (hydrochloride)| ChemScene 5mg  | >98%

ChemScene

(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist?and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction[2].In Vitro: Brain nicotinic acetylcholine receptors (nAChRs) is […]

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(S)-ZINC-3573| ChemScene 5mg  | >98%

ChemScene

(S)-ZINC-3573 is an inactive enantiomer of ZINC-3573. (R)-ZINC-3573 is a selective MRGPRX2 agonist. (S)-ZINC-3573 and (R)-ZINC3573 are effective and internally controlled probe-pairs for investigating the biology of primate-exclusive receptor.In Vitro: (S)-ZINC-3573 displays no activity on MRGPRX2 at concentrations below 100 μM. In Vivo: (R)-ZINC-3573阴性对照

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(Sar1)-Angiotensin II| ChemScene 1mg  | >98%

ChemScene

(Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes[2].In Vitro: (Sar1)-Angiotensin II (1 μM/day; 9 d) increases the total protein content in embryonic […]

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