TMAB is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetramethylammonium Dichloroiodate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetramethylammonium Hexafluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetramethylammonium perchlorate is used as an intermediate in organic and chemical synthesis. It is used as mobile phase in HPLC analysis and quantification of olanzapine, clozapine and N-desmethylclozapine. It acts as a supporting electrolyte in the electrochemical reduction of 1-bromodecane, 1-iodododecane, 2-iodooctane, and 2-bromooctane on a mercury cathode.

Tetramethylammonium fluoride tetrahydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetranitroblue tetrazolium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetrapropylammonium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetrapropylammonium hydroxide,40% w/w in water is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetrapropylammonium perruthenate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II)) is a luminescent indicator dye.

Phthalocyanine tetrasulfonic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetrazine-PEG7-amine hydrochloride is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).In Vitro:ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Tezacaftor (VX-661) is a F508del CFTR corrector. It helps CFTR protein reach the cell surface. However, Ivacaftor (VX-770, HY-13017), a CFTR potentiator, helps to prolong the opening time of cell surface CFTR protein channels. Tezacaftor combining with Ivacaftor, shows potent efficacy against cystic fibrosis and diseases with homozygous for the CFTR Phe508del mutation. Moreover, Elexacaftor […]

TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment.IC50 & Target: EC50: 2167 nM (Flag-TFEB nuclear translocation)In Vitro: TFEB […]

TFMB-(R)-2-HG, a cell membrane-permeable version of (R)-2-HG, is a carcinogenic factor in Acute myeloid leukemia (AML).TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cells differentiation in response to estrogen withdrawal.IC50 & Target: Carcinogenic factor

TFMB-(S)-2-HG is a potent inhibitor of the 5′-methylcytosine hydroxylase TET2. TFMB-(S)-2-HG also inhibits the EglN prolyl hydroxylases. TFMB-(S)-2-HG has the potential for the research of acute myeloid leukemia (AML).

TfR-T12 TFA is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range[2].In Vitro: TfR-T12 binds to the TfR and is subsequently internalized into TfR-expressing cells.TfR-T12 is a synthetic peptide obtained by phage display, and is able to bind a different site on TfRs compared with transferrin. TfR-T12 can be […]

TG 100713 is an inhibitor of PI3K, with IC50s of 24, 50, 165, and 215 nM for PI3Kδ, γ, α and β isoforms respectively.In Vitro: TG100713 (10 μM; 48 or 72 h) strongly inhibits endothelial cell (EC) proliferation.

TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM[2]. TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1. TG4-155 has an EP2 Schild KB of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 […]

TGFβ1-IN-1 (compound 42) is a potent, orally active TGF-β1 inhibitor. TGFβ1-IN-1 inhibits the upregulation of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in liver fibrosis disease studies.In Vitro: TGFβ1-IN-1 (compound 42) (0-20 μM, 72 h) inhibits the proliferation of TGF-β1 (5 ng/mL)-treated LX- 2 cells and inhibits LO2 cell viability with an […]

TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 inhibitor that binds a functional site in both miRNAs.

TH1020 is a potent and selective toll-like receptor 5 (TLR5)/flagellin complex antagonist with an IC50 of 0.85 μM. TH1020 inhbits flagellin-induced TLR5 signaling. TH1020 is inactive against TLR2, TLR3, TLR4, TLR7 and TLR8.IC50 & Target: IC50: 0.85 μM (toll-like receptor 5 (TLR5)/flagellin complex)In Vitro: TH1020 inhibits the downstream signaling transduction mediated by the formation of […]

TH10785 is a DNA glycosylase 1 (OGG1) activator, TH10785 can interact with the phenylalanine-319 and glycine-42 amino acids of OGG1 and increase the enzyme activity, generates β, δ-lyase enzymatic function. TH10785 can control the catalytic activity mediated by a nitrogen base within its molecular structure. TH10785 can be used for the research of various diseases […]

TH1217 (ZINC1775962367) is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19[2].IC50 & Target: IC50: 47 nM (dCTPase)In Vitro: TH1217 (compound 30) inhibits dCTPase and […]

TH5487 is a potent 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor with an IC50 of 342 nM. TH5487 stops OGG1 from recognizing its DNA substrate, inhibits DNA repair and modifies OGG1 chromatin dynamics, which results in the inhibition of proinflammatory pathway genes.In Vitro: TH5487 (5 μM; 1 hour) decreases TNFα- and LPS-induced proinflammatory gene expression to […]