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Pyridoxylamine dihydrochloride is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions.In Vitro: Pyridoxylamine (PM), a member of the B6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation.In Vivo: Pyridoxylamine limits the […]
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Pyridoxylidene-L-isoleucine Potassium Salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Pyrimethanil is an?anilinopyrimidine?and broad-spectrum?contact fungicide for the control of Botrytis spp. on a wide variety of crops. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in?Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection.In Vitro: Pyrimethanil is a strobilurin fungicide […]
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Pyrimorph is a fungicide with excellent antifungal activity against oomycetes.In Vitro: Pyrimorph inhibits different stages in the life cycle of P.capsici: mycelial growth (EC50 = 1.84 μg/mL), sporangia formation (EC50 = 0.17 μg/mL), zoospore release (EC50 = 4.92 μg/mL), cystospore germination (EC50 = 0.09 μg/mL).Pyrimorph exhibits 40.95% inhibition of oxygen consumption of intact mycelia at […]
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Pyripyropene A is a potent and selective sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) inhibitor, with an IC50 of 0.07 μM. Pyripyropene A attenuates hypercholesterolemia and atherosclerosis in vivo[2].IC50 & Target: IC50: 0.07 μM (ACAT2)In Vitro: Pyripyropene A (0-100 μM; 72 hours) exhibits anti-proliferative activity against HUVECs, and with an IC50 value of 1.8 […]
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Pyrithione, a Transition metal complexe, is a zinc ionophore that causes increased zinc levels within mammalian cells. Pyrithione has potent bactericidal and anti-fungal activity[2].
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Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection[2].In Vitro: Pyronaridine tetraphosphate (24 h) shows anti-P. falciparum activity with an IC50 value of 1.53-3.94 nM.In Vivo: Pyronaridine (57 mg/kg, oral administration, q.d. for 30 days) tetraphosphate reduces the parasitic burden in the Echinococcus […]
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Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor[2].In Vitro:Pyronin B (0-15 μM) inhibits channel activity of approximately 60% of small hydrophobic (SH) proteins at a concentration of 10 μM, and the Kd value […]
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Deuteroporphyrin dimethyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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