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(R)-Pirtobrutinib| ChemScene 100mg  | >98%

ChemScene

(R)-Pirtobrutinib ((R)-LOXO-305) is a less active enantiomer of Pirtobrutinib. Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations.

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(R)-Posenacaftor (sodium)| ChemScene 10mg  | >98%

ChemScene

(R)-Posenacaftor (R)-PTI-801) sodium is the R enantiomer of Posenacaftor. Posenacaftor is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of?CFTR?protein. Posenacaftor is used for the research of cystic fibrosis (CF).IC50 & Target: IC50: CFTRIn Vitro: Cystic fibrosis (CF) is an autosomal recessive disorder, caused by mutations of the cystic […]

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(R)-Praziquantel-d11| ChemScene 1mg  | >98%

ChemScene

(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer.IC50 & Target:5-HT2B receptorantischistosomalIn Vitro: (R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of […]

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(R)-Preclamol (hydrochloride)| ChemScene 50mg  | >98%

ChemScene

(R)-Preclamol hydrochloride ((+)-3-PPP hydrochloride) is the R-enantiomer of Preclamol hydrochloride. (R)-Preclamol hydrochloride is a DA agonist with autoreceptor as well as postsynaptic receptor stimulatory properties[2].

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(R)-Roscovitine| ChemScene 100mg  | >98%

ChemScene

(R)-Roscovitine (Seliciclib) is an orally bioavailable and selective CDKs inhibitor with IC50s of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5, Cdc2, and CDK2, respectively.IC50 & Target:IC50: 0.2 μM (CDK5), 0.65 μM (Cdc2), 0.7 μM (CDK2)In Vitro:(R)-Roscovitine (Seliciclib) displays high efficiency and high selectivity towards some cyclin-dependent kinases. The kinase specificity of Seliciclib is […]

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(R)-Terazosin| ChemScene 100mg  | >98%

ChemScene

(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent α1-adrenoceptor antagonist with Ki values of 6.51 nM, 1.01 nM and 1.97 nM for α1a, α1b and α1d-adrenoceptor, respectively.IC50 & Target: Ki: 6.51 nM (α1a-adrenoceptor), 1.01 nM (α1b-adrenoceptor) and 1.97 nM (α1d-adrenoceptor)In Vitro: (R)-Terazosin is low affinity for α2a, α2B and α2c-adrenoceptor with Ki […]

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