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N6-Benzyladenosine| ChemScene 1g  | >98%

ChemScene

N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma-.In Vitro: N6-benzyladenosine suppresses the clonogenic activity and the growth of different neoplastic cells[2].N6-benzyladenosine results cell morphology alteration and actin cytoskeleton disorganization in […]

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N6-Ethyladenosine| ChemScene 10mg  | >98%

ChemScene

N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively.IC50 & Target:Ki: 4.9 nM (hA1AR), 4.7 nM (hA3AR)In Vitro: N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA1AR and hA3AR over hA2AR (Ki, 8900±770 nM).

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nAChR agonist 1| ChemScene 5mg  | >98%

ChemScene

nAChR agonist 1 is a potent,?brain-permeable, and?orally?efficacious positive?allosteric?modulator?of α7?nicotinic?acetylcholine?receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 μM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease.In Vivo: Acute (single-dose) oral administration […]

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Nadolol| ChemScene 100mg  | >98%

ChemScene

Nadolol (SQ-11725) is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2). Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research[2].In Vitro: In human embryonic kidney 293 cells, (-)-Epigallocatechin gallate (EGCG) competitively inhibits OATP1A2-mediated uptake of Nadolol with a […]

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Nampt activator-2| ChemScene 5mg  | >98%

ChemScene

Nampt activator-2 (compound 34) is a potent NAMPT activator, with EC50 of 0.023 μM. Nampt activator-2 shows moderate activity against CYP2C9 (0.060 μM), 2D6 (0.41 μM) and 2C19 (0.59 μM).In Vitro:Nampt activator-2 (compound 34) (10 μM, 4 h) results in a marked increase of both NMN and NAD in A549 lung epithelial cells.In Vivo:Nampt activator-2 […]

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Naringenin chalcone| ChemScene 1mg  | >98%

ChemScene

Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) by chalcone isomerase. Naringenin chalcone has anti-inflammatory and antiallergic activities.

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Naringenin-d4| ChemScene 1mg  | >98%

ChemScene

Naringenin-d4 is the deuterated version of Naringenin (HY-N0100). Naringenin shows strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.

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