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Imagine the power of people with a common purpose to build relationships that create value for you and your business. This is ChemScene. Every day, our people work with you to ensure you have what you need to achieve your commercial and scientific pursuits. We make sure everything we do honors that relationship starting from our commitment to ensuring that our chemicals are held to the most rigorous quality standards in the world, to the way we engage with our customers and communities to do business responsibly.

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(R)-CR8 (trihydrochloride)| ChemScene 50mg  | >98%

ChemScene

(R)-CR8 (CR8) trihydrochloride, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 trihydrochloride inhibits CDK1/cyclin B (IC50=0.09 μM), CDK2/cyclin A (0.072 μM), CDK2/cyclin E (0.041 μM), CDK5/p25 (0.11 μM), CDK7/cyclin H (1.1 μM), CDK9/cyclin T (0.18 μM) and CK1δ/ε (0.4 μM). (R)-CR8 trihydrochloride induces apoptosis and has neuroprotective effect[2]. (R)-CR8 trihydrochloride acts as […]

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(R)-Funapide| ChemScene 10mg  | >98%

ChemScene

(R)-Funapide ((R)-TV 45070) is the less active R-enantiomer of Funapide. Funapide is a potent Nav1.7 sodium channel blocker that can be used for pain research.

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(R)-Irsenontrine| ChemScene 10mg  | >98%

ChemScene

(R)-Irsenontrine ((R)-E2027), the R-enantiomer of Irsenontrine (HY-132821), is a potent phosphodiesterase 9 (PDE9) inhibitor with an IC50 value of 0.041 μM. (R)-Irsenontrine can be used for the research of neurological diseases.

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(R)-Lanicemine| ChemScene 5mg  | >98%

ChemScene

(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1?μM for NMDA receptor; IC50s of 4-7?μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.

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(R)-M8891| ChemScene 10mg  | >98%

ChemScene

(R)-M8891 (compound R-9) is a less active isomer of M8891. M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor.

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