ChemScene

Imagine the power of people with a common purpose to build relationships that create value for you and your business. This is ChemScene. Every day, our people work with you to ensure you have what you need to achieve your commercial and scientific pursuits. We make sure everything we do honors that relationship starting from our commitment to ensuring that our chemicals are held to the most rigorous quality standards in the world, to the way we engage with our customers and communities to do business responsibly.

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(11bS)-N,N-Bis[(1R)-1-(1-naphthalenyl)ethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine| ChemScene 50mg | >98%

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(11bS)-N,N-Bis[(1S)-1-(1-naphthalenyl)ethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine| ChemScene 250mg | >98%

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(11bS)-N,N-Bis[(1S)-1-(4-methoxyphenyl)ethyl]-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine| ChemScene 1g | >98%

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(11bS)-N,N-Diethyl-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine| ChemScene 1g | >98%

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(11bS)-N,N-Dimethyl-2,6-diphenyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine| ChemScene 100mg | >98%

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(11R,12R)-9,10-Dihydro-9,10-ethanoanthracene-11,12-diamine| ChemScene 250mg | >98%

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(12E,14E,21E)-2,3,9,10,16,17,23,24-octakis(octyloxy)-13H,29H-phthalocyanine| ChemScene 250mg | >98%

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(12Z)-henicosa-2,12-dienoic acid| ChemScene 5mg | >98%

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(13bR)-5,7-Dihydro-2,8-dimethoxy-3H-cyclopenta[6,7]cycloocta[2,1-a:3,4-a’]dinaphthalene| ChemScene 100mg | >98%

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(16aR)-1,16-Bis(diphenylphosphino)-6,7,8,9,10,11-hexahydrodibenzo[b,d][1,6]dioxacyclododecine| ChemScene 1g | >98%

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(1aS,3aR,6R,7aR,7bS)-6-Phenylhexahydrooxireno[2′,3′:4,5]pyrano[3,2-d][1,3]dioxine| ChemScene 1g | >98%

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(1aα,6β,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-ol| ChemScene 1g | >98%

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(1E,1’E)-1,1′-(1,4-Phenylene)bis(N-(pyridin-4-yl)methanimine)| ChemScene 5g | >98%

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(1E,1’E)-N,N’-(phenylmethylene)bis(1-phenylmethanimine)| ChemScene 5g | >98%

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(1E,2E)-3-phenyl-N-(4H-1,2,4-triazol-4-yl)prop-2-en-1-imine| ChemScene 1g | >98%

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(1E,3E)-1-(4-fluorophenyl)-2-methylpent-1-en-3-one oxime| ChemScene 1g | >98%

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(1E,4E)-1-(2,4-dimethoxyphenyl)-5-(dimethylamino)penta-1,4-dien-3-one| ChemScene 500mg | >98%

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(1E,4E)-1-(4-chlorophenyl)-5-(dimethylamino)penta-1,4-dien-3-one| ChemScene 1g | >98%

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(1E,4E)-1-(dimethylamino)-5-(4-methoxyphenyl)penta-1,4-dien-3-one| ChemScene 1g | >98%

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(1E,4E)-1-(dimethylamino)-5-phenylpenta-1,4-dien-3-one| ChemScene 1g | >98%

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(1e)-1-(1-ethyl-3,5-dimethyl-1h-pyraZol-4-yl)ethanone oxime| ChemScene 2500mg | >98%

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(1e)-1-(Dimethylamino)-4,4-dimethylpent-1-en-3-one| ChemScene 1g | >98%

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(1e)-1-Bromocyclooct-1-ene| ChemScene 500mg | >98%

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(1e)-3,3,3-Trifluoro-1-nitroprop-1-ene| ChemScene 500mg | >98%

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(1E)-3,4-Dihydro-1(2H)-naphthalenone-O-[(4-methylphenyl)sulfonyl]oxime| ChemScene 1g | >98%

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(1E)-CFI-400437 (dihydrochloride)| ChemScene 25mg | >98%

ChemScene

(1E)-CFI-400437 dihydrochloride is a potent PLK4 (IC50= 0.6 nM) inhibitor and selective against other members of the PLK family (>10 μM). (1E)-CFI-400437 dihydrochloride inhibits Aurora A, Aurora B, KDR and FLT-3 with IC50s of 0.37, 0.21, 0.48, and 0.18 μM, respectively. Antiproliferative activity.In Vivo: (1E)-CFI-400437 (25 mg/kg; intraperitoneal injection; daily for 21 days) dihydrochloride shows […]

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