BOC Sciences
(-)-Nebivolol-[d4] Hydrochloride, is the labelled analogue of Nebivolol. Nebivolol, a highly selective β1-adrenergic receptor inhibitor, has vasodilatory effect so that could be effective against hypertension. It was just withdrawed a Phase II/III trial for Hypertension in patients with chronic obstructive pulmonary disease.
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(−)-Neplanocin A potently and irreversibly inactivates SAH hydrolase (Ki = 8.39 nM). It has antitumor activity against mouse leukemia L1210 cells and broad-spectrum antiviral activity. Neplanocin A is more potent against vesicular stomatitis than the reversible SAH hydrolase inhibitor 3-deazaneplanocin (ID50 = 0.07 and 0.3 μg/ml, respectively).
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(-)-Noe’s reagent is a chiral resolution reagent to separate racemic compounds into different mirror isomers and is an important tool for the production of optically active drugs.
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(-)-NPPCC
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| 98%
BOC Sciences
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(-)-O-Desmethyl Tramadol-[d6], is the labelled analogue of Desmetramadol. Desmetramadol, also known as O-desmethyltramadol, is an opioid analgesic and the main active metabolite of tramadol.
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BOC Sciences
(-)-O,O’-Di-p-toluoyl-L-tartaric Acid (CAS# 32634-66-5) is a useful reagent for the preparation of the upadacitinib salt compound.
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BOC Sciences
BOC Sciences
(-)-O,O’-Dibenzylcoclaurine Hydrochloride is an intermediate in the synthesis of (+)-S-N-Methylcoclaurine Hydrochloride, (M294325), a structure analog of Coclaurine (C633550), a benzyltetrahydroisoquinoline alkaloid extracted from Magnolia salicifolia.
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(-)-OSU-[d7]
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| Purity Not Available
BOC Sciences
(-)-OSU-[d7], is the labelled analogue of (-)-OSU. (-)-OSU is a compound which acts as a partial agonist at both dopamine D2 receptors and 5-HT2A receptors.
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BOC Sciences
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(-)-PSI Reagent
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| Purity Not Available
BOC Sciences
(-)-PSI Reagent is used in the lab for stereocontrolled synthesis of phosphorothioate oligonucleotides, stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).
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BOC Sciences
(-)-Quinpirole hydrochloride is a selective dopamine D2 receptor agonist, with high affinity for the D2 and D3 dopamine receptor subtypes (Ki values are 4.8, ~24, ~30 and 1900 nM at D2, D3, D4 and D1 receptors respectively).
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BOC Sciences
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(-)-Riboflavin 5-phosphate-[13C4,15N2] is the labelled analogue of FMN. FMN is a biological molecule produced by riboflavin kinase from riboflavin (vitamin B2). It has a role as a coenzyme, a bacterial metabolite, a human metabolite, a mouse metabolite and a cofactor.
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BOC Sciences
It is the less common optical isomer of the mycotoxin, (+)-rugulosin. It is first isolated from myrothecium verrucaria. It is a mycotoxin with antiviral activity.
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BOC Sciences
(-)-Sandaracopimaric Acid is a seamane diterpene found in the leaves of Wollemia nobilis and is used in self-defense against herbivores.
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BOC Sciences
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(-)-Scopolamine-[d3] hydrochloride is the labelled analogue of (-)-Scopolamine hydrochloride, which is a competitive non-selective mAChR M (muscarinic acetylcholine) antagonist.
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BOC Sciences
A member of flavagline family of natural products from the genus of Aglaia, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7; 5’myc-UTR-LUC inhibtior with IC50 of 0.8 nM.
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BOC Sciences
(-)-Sparteine sulfate pentahydrate is an alkaloid compound which could be used as in the treatment of antiarrhythmic by blocking sodium channel.
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BOC Sciences
(-)-Syringaresinol is isolated from the rhizomes of Polygonatum kingianum. DL-Syringaresinol inhibits the proliferation of human promyelocytic HL-60 cells through G(1) arrest and induction of apoptosis, may be a potential chemotherapeutic agent for the treatment of cancer.
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BOC Sciences
(-)-Syringaresnol-4-O-beta-D-apiofuranosyl-(1->2)-beta-D-glucopyranoside can be found in the Albizia julibrissin Duraz.
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BOC Sciences
(-)-Tetrabenazine is one of Tetrabenazine impurities. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders.
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