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3-bromo-4-chlorotoluene (CAS# 57310-39-1) is a useful synthetic intermediate. It can be used to synthesize N-heterocycle-fused phenanthridines via palladium-catalyzed tandem N-H/C-H arylation of aryl-N-heteroarenes with dihaloarenes. It can also be used to synthesize substituted fluorenes.
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3-Bromo-4-cyanopyridine (CAS# 13958-98-0) is used in the synthesis of nicotinic receptor ligands which have application towards diseases such as nicotinic addiction,, neurodegenerative and cognitive disorders. It is also used in the synthesis of orally bioavailable cannabinoid receptor 2 agonists for use as analgesic and anti-inflammatory agents.
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3-Bromo-4-fluorobenzoic acid (CAS# 1007-16-5) is a building block used in the synthesis of a highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.
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3-Bromo-4-fluorophenylacetic Acid (CAS# 194019-11-9) is usedas a reagent in the preparation of 4-oxo-1,4-dihydripyridine-3-carboxamide derivatives as inhibitors of Axl tyrosine kinase and anticancer agents.
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