AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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Physil chloride 250 mg  | >98%

AdipoGen Life Sciences

It is known that phenol and p-cresol are promoters of skin tumors and also urinary excretion of phenol and p-cresol is increased by exposure to benzene, which has hemopoietic toxicity, and toluene, respectively. Therefore, the determination of phenol and p-cresol is important in clinical chemistry and toxicology. Because phenol and p-cresol are present in urine […]

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Piceatannol 1 mg  | >98%

AdipoGen Life Sciences

Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. Inhibits the tyrosine phosphorylation of STAT3 and STAT5. Potent apoptosis inducer. Potent anticancer compound. Suppresses NF-kB activation through IkBalpha kinase inhibition. Activator of human deacetylase SIRT1 (sirtuin 1). Potent antioxidant with anti-proliferative, anti-inflammatory and cardioprotective properties. […]

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Piceatannol 5 mg  | >98%

AdipoGen Life Sciences

Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. Inhibits the tyrosine phosphorylation of STAT3 and STAT5. Potent apoptosis inducer. Potent anticancer compound. Suppresses NF-kB activation through IkBalpha kinase inhibition. Activator of human deacetylase SIRT1 (sirtuin 1). Potent antioxidant with anti-proliferative, anti-inflammatory and cardioprotective properties. […]

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Piceatannol 25 mg  | >98%

AdipoGen Life Sciences

Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. Inhibits the tyrosine phosphorylation of STAT3 and STAT5. Potent apoptosis inducer. Potent anticancer compound. Suppresses NF-kB activation through IkBalpha kinase inhibition. Activator of human deacetylase SIRT1 (sirtuin 1). Potent antioxidant with anti-proliferative, anti-inflammatory and cardioprotective properties. […]

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Pifithrin-alpha . HBr 5 mg  | >98%

AdipoGen Life Sciences

p53 inhibitor. Reversibly blocks p53-dependent transcriptional activation. Tool to combat side effects of cancer therapy. Apoptosis inhibitor.

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Pifithrin-alpha . HBr 10 mg  | >98%

AdipoGen Life Sciences

p53 inhibitor. Reversibly blocks p53-dependent transcriptional activation. Tool to combat side effects of cancer therapy. Apoptosis inhibitor.

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Pifithrin-alpha . HBr 25 mg  | >98%

AdipoGen Life Sciences

p53 inhibitor. Reversibly blocks p53-dependent transcriptional activation. Tool to combat side effects of cancer therapy. Apoptosis inhibitor.

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Pikromycin 1 mg  | >95%

AdipoGen Life Sciences

Antibiotic. 14-Membered macrolide. Active against Gram-positive bacteria including mycobacteria. Prolyl endopeptidase (PREP) inhibitor.

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Pikromycin 5 mg  | >95%

AdipoGen Life Sciences

Antibiotic. 14-Membered macrolide. Active against Gram-positive bacteria including mycobacteria. Prolyl endopeptidase (PREP) inhibitor.

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Pimprinine 1 mg  | >98%

AdipoGen Life Sciences

Indole alkaloid. Monoamine oxidase inhibitor (MAOI). Antiepileptic (anticonvulsant) compound. Inhibitor of platelet aggregation and thromboxane A2 synthesis. Weak antifungal and antituberculosis activity. Useful as lead structure for potent antifungal substances.

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Pimprinine 5 mg  | >98%

AdipoGen Life Sciences

Indole alkaloid. Monoamine oxidase inhibitor (MAOI). Antiepileptic (anticonvulsant) compound. Inhibitor of platelet aggregation and thromboxane A2 synthesis. Weak antifungal and antituberculosis activity. Useful as lead structure for potent antifungal substances.

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Pioglitazone 1 mg  | >98%

AdipoGen Life Sciences

Thiazolidinedione (TZD) reference compound. Selective PPARgamma agonist. Selectively activates PPARgamma-1. Anti-diabetic , decreasing insulin resistance in adipose tissue. Is about one tenth as potent as rosiglitazone. Lipid metabolism modulator. Estrogen synthesis inhibitor. NF-kappaB inhibitor. Neuroprotective.

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Pioglitazone 5 mg  | >98%

AdipoGen Life Sciences

Thiazolidinedione (TZD) reference compound. Selective PPARgamma agonist. Selectively activates PPARgamma-1. Anti-diabetic , decreasing insulin resistance in adipose tissue. Is about one tenth as potent as rosiglitazone. Lipid metabolism modulator. Estrogen synthesis inhibitor. NF-kappaB inhibitor. Neuroprotective.

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Pioglitazone 25 mg  | >98%

AdipoGen Life Sciences

Thiazolidinedione (TZD) reference compound. Selective PPARgamma agonist. Selectively activates PPARgamma-1. Anti-diabetic , decreasing insulin resistance in adipose tissue. Is about one tenth as potent as rosiglitazone. Lipid metabolism modulator. Estrogen synthesis inhibitor. NF-kappaB inhibitor. Neuroprotective.

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Piperlongumine 10 mg  | >97%

AdipoGen Life Sciences

Cytotoxic against tumor cell lines. Induces necrosis and apoptosis in cancer cells. Shows anti-platelet aggregation activity possibly by inhibition of cyclooxgenase activity and a decrease in thromboxane A2 formation. Shows significant anxiolytic and antidepressant activities. Promotes adipogenesis of 3T3-L1 cells. Induces in vivo and in vitro mutagenicity in eukaryotic models. Selectively kills cancer cells by […]

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Piperlongumine 50 mg  | >97%

AdipoGen Life Sciences

Cytotoxic against tumor cell lines. Induces necrosis and apoptosis in cancer cells. Shows anti-platelet aggregation activity possibly by inhibition of cyclooxgenase activity and a decrease in thromboxane A2 formation. Shows significant anxiolytic and antidepressant activities. Promotes adipogenesis of 3T3-L1 cells. Induces in vivo and in vitro mutagenicity in eukaryotic models. Selectively kills cancer cells by […]

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Piroctone olamine 100 mg  | >99%

AdipoGen Life Sciences

Antimycotic compound with antidandruff efficacy. Selectively induced apoptosis in various human and murine myeloma and lymphoma cell lines. Compound can be used as analytical reference material.

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Piroctone olamine 500 mg  | >99%

AdipoGen Life Sciences

Antimycotic compound with antidandruff efficacy. Selectively induced apoptosis in various human and murine myeloma and lymphoma cell lines. Compound can be used as analytical reference material.

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PJ-34 1 mg  | >98%

AdipoGen Life Sciences

Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells.

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PJ-34 5 mg  | >98%

AdipoGen Life Sciences

Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells.

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PJ-34 25 mg  | >98%

AdipoGen Life Sciences

Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells.

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PK 11195 10 mg  | >98%

AdipoGen Life Sciences

Selective peripheral benzodiazepine antagonist. Apoptosis enhancer. Glucose-induced insulin secretion inhibitor. Induces mitochondria cytochrome c release. Anticancer compound. Antiproliferative. Pharmacological tool in autophagy.

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PK 11195 50 mg  | >98%

AdipoGen Life Sciences

Selective peripheral benzodiazepine antagonist. Apoptosis enhancer. Glucose-induced insulin secretion inhibitor. Induces mitochondria cytochrome c release. Anticancer compound. Antiproliferative. Pharmacological tool in autophagy.

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PLX4720 5 mg  | >99%

AdipoGen Life Sciences

Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.

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PLX4720 25 mg  | >99%

AdipoGen Life Sciences

Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.

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PMA 1 mg  | >98%

AdipoGen Life Sciences

Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor […]

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PMA 5 mg  | >98%

AdipoGen Life Sciences

Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor […]

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PMA 10 mg  | >98%

AdipoGen Life Sciences

Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor […]

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PMA 25 mg  | >98%

AdipoGen Life Sciences

Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor […]

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PMPH 1 mg  | >98%

AdipoGen Life Sciences

Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =11nM). Displays high selectivity over HDAC1 (IC50=1.5µM). Neuroprotective. Effectively prevents neuronal cell death upon oxidative stress induction by HCA and selectively induces cellular alpha-tubulin hyperacetylation. HDAC6 deacetylates tubulin, HSP90 and the core histones (H2A, H2B, H3, H4). Histone deacetylases act via the formation of large […]

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PMPH 5 mg  | >98%

AdipoGen Life Sciences

Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =11nM). Displays high selectivity over HDAC1 (IC50=1.5µM). Neuroprotective. Effectively prevents neuronal cell death upon oxidative stress induction by HCA and selectively induces cellular alpha-tubulin hyperacetylation. HDAC6 deacetylates tubulin, HSP90 and the core histones (H2A, H2B, H3, H4). Histone deacetylases act via the formation of large […]

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Podophyllotoxin 100 mg  | >98%

AdipoGen Life Sciences

Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.

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Poly(D-lactide) 100 mg  | <0.5%

AdipoGen Life Sciences

Poly(D-lactide) (PDLA), a polymer of a stereospecific cyclic di-ester of lactic acid, is used in biomaterial research for the development of devices such as therapeutic drug delivery vessels. Poly(D-lactide) is used for the preparation of microparticles and resorbable polylactide scaffolds.

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Poly(D-lactide) 250 mg  | <0.5%

AdipoGen Life Sciences

Poly(D-lactide) (PDLA), a polymer of a stereospecific cyclic di-ester of lactic acid, is used in biomaterial research for the development of devices such as therapeutic drug delivery vessels. Poly(D-lactide) is used for the preparation of microparticles and resorbable polylactide scaffolds.

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Poly(D-lactide) 2.5 g  | <0.5%

AdipoGen Life Sciences

Poly(D-lactide) (PDLA), a polymer of a stereospecific cyclic di-ester of lactic acid, is used in biomaterial research for the development of devices such as therapeutic drug delivery vessels. Poly(D-lactide) is used for the preparation of microparticles and resorbable polylactide scaffolds.

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Ponasterone A 1 mg  | >95%

AdipoGen Life Sciences

A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Analog of ecdysone with similar properties to muristerone A. Functional, reliable and economical substitute for muristerone A as an inducer for the ecdysone-inducible mammalian expression system. Induces expression of beta-galactosidase to levels similar to those obtained with muristerone A induction. Potent compound for ecdysteroid activity. […]

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Ponasterone A 5 mg  | >95%

AdipoGen Life Sciences

A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Analog of ecdysone with similar properties to muristerone A. Functional, reliable and economical substitute for muristerone A as an inducer for the ecdysone-inducible mammalian expression system. Induces expression of beta-galactosidase to levels similar to those obtained with muristerone A induction. Potent compound for ecdysteroid activity. […]

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Ponasterone A 25 mg  | >95%

AdipoGen Life Sciences

A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Analog of ecdysone with similar properties to muristerone A. Functional, reliable and economical substitute for muristerone A as an inducer for the ecdysone-inducible mammalian expression system. Induces expression of beta-galactosidase to levels similar to those obtained with muristerone A induction. Potent compound for ecdysteroid activity. […]

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