AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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Parecoxib 25 mg  | >98%

AdipoGen Life Sciences

Potent and selective COX-2 inhibitor. Water-soluble amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib. Has anti-inflammatory, analgesic, and antipyretic activities. Upon administration, parecoxib is hydrolyzed by hepatic carboxyesterases to its active form, valdecoxib.

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PARG Inhibitor PDD00017273 1 mg  | >98%

AdipoGen Life Sciences

Human poly(ADP-ribose) glycohydrolase (PARG) inhibitor for in vitro studies. Inhibits human recombinant PARG enzymes (IC50=26nM) and PARG in cell assays (IC50=37nM). Inactive against related glycohydrolases ARH3 and PARP1s (IC50>30µM). Showed no cytotoxicity (IC50>30µM). Poly(ADP ribose) glycohydrolase (PARG) is a critical component in the repair of single strand DNA breaks and therefore a target in cancer […]

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PARG Inhibitor PDD00017273 5 mg  | >98%

AdipoGen Life Sciences

Human poly(ADP-ribose) glycohydrolase (PARG) inhibitor for in vitro studies. Inhibits human recombinant PARG enzymes (IC50=26nM) and PARG in cell assays (IC50=37nM). Inactive against related glycohydrolases ARH3 and PARP1s (IC50>30µM). Showed no cytotoxicity (IC50>30µM). Poly(ADP ribose) glycohydrolase (PARG) is a critical component in the repair of single strand DNA breaks and therefore a target in cancer […]

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Parthenolide 10 mg  | >98%

AdipoGen Life Sciences

Anticancer and antiangiogenic compound. Induces apoptosis, cell cycle arrest and autophagy in various cancer cell lines. At low concentrations acts as antioxidant reducing oxidative stress generated through the TCR signaling pathway. At high concentration induces O2- and causes oxidative-stress-mediated apoptosis. Potent anti-inflammatory and anti-atherosclerotic agent. NF-kappaB inhibitor by directly targeting IkappaB kinase. Inhibits STAT-mediated anti-apoptotic […]

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Parthenolide 50 mg  | >98%

AdipoGen Life Sciences

Anticancer and antiangiogenic compound. Induces apoptosis, cell cycle arrest and autophagy in various cancer cell lines. At low concentrations acts as antioxidant reducing oxidative stress generated through the TCR signaling pathway. At high concentration induces O2- and causes oxidative-stress-mediated apoptosis. Potent anti-inflammatory and anti-atherosclerotic agent. NF-kappaB inhibitor by directly targeting IkappaB kinase. Inhibits STAT-mediated anti-apoptotic […]

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Parthenolide 250 mg  | >98%

AdipoGen Life Sciences

Anticancer and antiangiogenic compound. Induces apoptosis, cell cycle arrest and autophagy in various cancer cell lines. At low concentrations acts as antioxidant reducing oxidative stress generated through the TCR signaling pathway. At high concentration induces O2- and causes oxidative-stress-mediated apoptosis. Potent anti-inflammatory and anti-atherosclerotic agent. NF-kappaB inhibitor by directly targeting IkappaB kinase. Inhibits STAT-mediated anti-apoptotic […]

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Paxilline 1 mg  | >95%

AdipoGen Life Sciences

Tremorgenic. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)). Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor. Liver X receptor (LXRalpha and LXRbeta; NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays. Anticonvulsant. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis. Shown to […]

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Paxilline 5 mg  | >95%

AdipoGen Life Sciences

Tremorgenic. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)). Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor. Liver X receptor (LXRalpha and LXRbeta; NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays. Anticonvulsant. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis. Shown to […]

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PD 150,606 5 mg  | >98%

AdipoGen Life Sciences

Cell permeable and selective calpain-1 and -2 inhibitor. Interacts with calcium-binding domain of calpain. Neuroprotective. Ca2+-permeable AMPA receptor inhibitor. Apoptosis inhibitor Autophagy activator by preventing cleavage of ATG5

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PD 150,606 25 mg  | >98%

AdipoGen Life Sciences

Cell permeable and selective calpain-1 and -2 inhibitor. Interacts with calcium-binding domain of calpain. Neuroprotective. Ca2+-permeable AMPA receptor inhibitor. Apoptosis inhibitor Autophagy activator by preventing cleavage of ATG5

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PD 184,352 1 mg  | >95%

AdipoGen Life Sciences

MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer.

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PD 184,352 5 mg  | >95%

AdipoGen Life Sciences

MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer.

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PD 98,059 1 mg  | >98%

AdipoGen Life Sciences

Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor. Blocks the phosphorylation and activation of the MAP kinase pathway. T cell activation inhibitor. Inhibits cell growth and cell proliferation of several cancer cells.

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PD 98,059 5 mg  | >98%

AdipoGen Life Sciences

Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor. Blocks the phosphorylation and activation of the MAP kinase pathway. T cell activation inhibitor. Inhibits cell growth and cell proliferation of several cancer cells.

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PD 98,059 10 mg  | >98%

AdipoGen Life Sciences

Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor. Blocks the phosphorylation and activation of the MAP kinase pathway. T cell activation inhibitor. Inhibits cell growth and cell proliferation of several cancer cells.

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PD 98,059 50 mg  | >98%

AdipoGen Life Sciences

Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor. Blocks the phosphorylation and activation of the MAP kinase pathway. T cell activation inhibitor. Inhibits cell growth and cell proliferation of several cancer cells.

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Pellitorine 1 mg  | >97%

AdipoGen Life Sciences

Tingling-inducing agent. Excellent stable model compound for sensory studies. Exerts same profile as the unstable compound hydroxy-alpha-sanshool. Shows larvicidal, antimycobacterial and antituberculosis activity. alpha-Glucosidase inhibitor used in diabetes mellitus, cancer, infection and inflammatory research. ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Potential anti-cancer lead compound. Anti-thrombotic. Anti-septic. Antiprotozoal, antimalarial activity.

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Pellitorine 5 mg  | >97%

AdipoGen Life Sciences

Tingling-inducing agent. Excellent stable model compound for sensory studies. Exerts same profile as the unstable compound hydroxy-alpha-sanshool. Shows larvicidal, antimycobacterial and antituberculosis activity. alpha-Glucosidase inhibitor used in diabetes mellitus, cancer, infection and inflammatory research. ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Potential anti-cancer lead compound. Anti-thrombotic. Anti-septic. Antiprotozoal, antimalarial activity.

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Pellitorine 25 mg  | >97%

AdipoGen Life Sciences

Tingling-inducing agent. Excellent stable model compound for sensory studies. Exerts same profile as the unstable compound hydroxy-alpha-sanshool. Shows larvicidal, antimycobacterial and antituberculosis activity. alpha-Glucosidase inhibitor used in diabetes mellitus, cancer, infection and inflammatory research. ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Potential anti-cancer lead compound. Anti-thrombotic. Anti-septic. Antiprotozoal, antimalarial activity.

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Penicillide 250 µg  | >95%

AdipoGen Life Sciences

Plant growth inhibitor. Acyl-CoA-cholesterol acyltransferase (ACAT) inhibitor. Anticancer compound. Cytotoxic. Non-peptidic oxytocin receptor antagonist. Calpain inhibitor.

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Penicillide 1 mg  | >95%

AdipoGen Life Sciences

Plant growth inhibitor. Acyl-CoA-cholesterol acyltransferase (ACAT) inhibitor. Anticancer compound. Cytotoxic. Non-peptidic oxytocin receptor antagonist. Calpain inhibitor.

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Pentabromopseudilin 500 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial, cytotoxic, herbicidal and antimalarial compound. Human lipoxygenase inhibitor. Potent myosin ATPase inhibitor. Inhibitor of the non-mevalonate pathway enzyme IspD.

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Pentabromopseudilin 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial, cytotoxic, herbicidal and antimalarial compound. Human lipoxygenase inhibitor. Potent myosin ATPase inhibitor. Inhibitor of the non-mevalonate pathway enzyme IspD.

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Pentabromopseudilin 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial, cytotoxic, herbicidal and antimalarial compound. Human lipoxygenase inhibitor. Potent myosin ATPase inhibitor. Inhibitor of the non-mevalonate pathway enzyme IspD.

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Penthiopyrad 25 mg  | >98%

AdipoGen Life Sciences

Systemic broad spectrum fungicide. Interferes with fungal respiration by inhibition of Complex II: succinate-dehydrogenase (SDH). Compound can be used as analytical reference material.

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Pepstatin A 25 mg  | >98%

AdipoGen Life Sciences

Tight-binding, reversible, highly selective inhibitor of acid proteases (aspartyl peptidases), like pepsin, gastricsin, cathepsin E and D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Does not inhibit thiol proteases, neutral proteases or serine proteases. Widely used as a research tool in studies of protease mechanisms and biological functions. Solubilized gamma-secretase and retroviral protease inhibitor. […]

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Pepstatin A 100 mg  | >98%

AdipoGen Life Sciences

Tight-binding, reversible, highly selective inhibitor of acid proteases (aspartyl peptidases), like pepsin, gastricsin, cathepsin E and D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Does not inhibit thiol proteases, neutral proteases or serine proteases. Widely used as a research tool in studies of protease mechanisms and biological functions. Solubilized gamma-secretase and retroviral protease inhibitor. […]

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Pepstatin A 5 mg  | >98%

AdipoGen Life Sciences

Tight-binding, reversible, highly selective inhibitor of acid proteases (aspartyl peptidases), like pepsin, gastricsin, cathepsin E and D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Does not inhibit thiol proteases, neutral proteases or serine proteases. Widely used as a research tool in studies of protease mechanisms and biological functions. Solubilized gamma-secretase and retroviral protease inhibitor. […]

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PF-2545920 1 mg  | >98%

AdipoGen Life Sciences

Potent and selective phosphodiesterase 10A (PDE10A) inhibitor (IC50=1.26nM) in vitro and in vivo. PDE10A is a cGMP and cAMP degrading PDE isozyme with neurological importance and was shown to be implicated in the regulation of energy homeostasis. Inhibition of PDE10A leads to interference of the breakdown of the secondary messenger cAMP and cGMP. Anti-psychotic agent. […]

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PF-2545920 5 mg  | >98%

AdipoGen Life Sciences

Potent and selective phosphodiesterase 10A (PDE10A) inhibitor (IC50=1.26nM) in vitro and in vivo. PDE10A is a cGMP and cAMP degrading PDE isozyme with neurological importance and was shown to be implicated in the regulation of energy homeostasis. Inhibition of PDE10A leads to interference of the breakdown of the secondary messenger cAMP and cGMP. Anti-psychotic agent. […]

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PF-2545920 25 mg  | >98%

AdipoGen Life Sciences

Potent and selective phosphodiesterase 10A (PDE10A) inhibitor (IC50=1.26nM) in vitro and in vivo. PDE10A is a cGMP and cAMP degrading PDE isozyme with neurological importance and was shown to be implicated in the regulation of energy homeostasis. Inhibition of PDE10A leads to interference of the breakdown of the secondary messenger cAMP and cGMP. Anti-psychotic agent. […]

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Phenol red sodium salt 1 g  | Purity Not Available

AdipoGen Life Sciences

Water soluble pH indicator used in the 6.8 (yellow) to 8.2 (red) range and frequently used in cell biology laboratories. Widely used as cell tissue culture pH marker. A small amount of phenol red added to the growth medium will have a pink-red color under normal conditions. Typically, 15 mg/l are used for cell culture. […]

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Phenol red sodium salt 10 g  | Purity Not Available

AdipoGen Life Sciences

Water soluble pH indicator used in the 6.8 (yellow) to 8.2 (red) range and frequently used in cell biology laboratories. Widely used as cell tissue culture pH marker. A small amount of phenol red added to the growth medium will have a pink-red color under normal conditions. Typically, 15 mg/l are used for cell culture. […]

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Phenol red sodium salt 50 g  | Purity Not Available

AdipoGen Life Sciences

Water soluble pH indicator used in the 6.8 (yellow) to 8.2 (red) range and frequently used in cell biology laboratories. Widely used as cell tissue culture pH marker. A small amount of phenol red added to the growth medium will have a pink-red color under normal conditions. Typically, 15 mg/l are used for cell culture. […]

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Phenylmethylene hydantoin [PMH] 1 mg  | >97%

AdipoGen Life Sciences

Anticancer compound. Chemopreventive. Shows anti-metastatic activity in prostate cancer cells through enhancement of cell-cell adhesion. Anti-invasive compound. Glycogen synthase kinase-3beta (GSK-3 beta) inhibitor.

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Phomoxanthone A 5 mg  | >97%

AdipoGen Life Sciences

Mycotoxin Antibacterial against Gram-positive bacteria. Shows antimalarial and antitubercular activity. Anticancer compound. Cytotoxic against several cancer cell lines (pro-apoptotic activity). Active against plant pathogene fungi (e.g. P. oryza, Phyt. infestans). Activator of murine T lymphocytes, NK cells and macrophages.

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Phomoxanthone A 1 mg  | >97%

AdipoGen Life Sciences

Anticancer compound. Shows antimalarial and antitubercular activity. Cytotoxic against several cancer cell lines. Antibacterial against Gram-positive bacteria and antifungal. Activator of murine T lymphocytes, NK cells and macrophages.

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Physil chloride 50 mg  | >98%

AdipoGen Life Sciences

It is known that phenol and p-cresol are promoters of skin tumors and also urinary excretion of phenol and p-cresol is increased by exposure to benzene, which has hemopoietic toxicity, and toluene, respectively. Therefore, the determination of phenol and p-cresol is important in clinical chemistry and toxicology. Because phenol and p-cresol are present in urine […]

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