AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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N-tert-Butyl-alpha-phenylnitrone [PBN] 1 g  | >98%

AdipoGen Life Sciences

Cell permeable spin trap commonly used in free radical research for both in vivo and in vitro studies. It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects. PBN has been shown to inhibit LPS-induced NF-kappaB DNA binding activity, inhibit COX-2 catalytic activity, inhibit lipid peroxidation in rat liver […]

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N-tert-Butyl-alpha-phenylnitrone [PBN] 5 g  | >98%

AdipoGen Life Sciences

Cell permeable spin trap commonly used in free radical research for both in vivo and in vitro studies. It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects. PBN has been shown to inhibit LPS-induced NF-kappaB DNA binding activity, inhibit COX-2 catalytic activity, inhibit lipid peroxidation in rat liver […]

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N-Tetradecanoyl-DL-homoserine lactone 10 mg  | >97%

AdipoGen Life Sciences

N-Tetradecanoyl-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter […]

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N-Tetradecanoyl-DL-homoserine lactone 50 mg  | >97%

AdipoGen Life Sciences

N-Tetradecanoyl-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter […]

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N-Tetradecanoyl-L-homoserine lactone 10 mg  | >97%

AdipoGen Life Sciences

N-Tetradecanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter […]

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N-Tetradecanoyl-L-homoserine lactone 50 mg  | >97%

AdipoGen Life Sciences

N-Tetradecanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter […]

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N,N-Dimethyl-6-propionyl-2-naphthylamine 25 mg  | >98%

AdipoGen Life Sciences

N,N-dimethyl-6-propionyl-2-naphthylamine (prodan) has both an electron-donor and an electron-acceptor substituent, resulting in a large excited-state dipole moment and extensive solvent polarity-dependent fluorescence shifts. When prodan is incorporated into membranes, their fluorescence spectra are sensitive to the physical state of the surrounding phospholipids. In membranes, prodan appears to localize at the surface, although Fourier transform infrared […]

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N,N-Dimethyl-6-propionyl-2-naphthylamine 50 mg  | >98%

AdipoGen Life Sciences

N,N-dimethyl-6-propionyl-2-naphthylamine (prodan) has both an electron-donor and an electron-acceptor substituent, resulting in a large excited-state dipole moment and extensive solvent polarity-dependent fluorescence shifts. When prodan is incorporated into membranes, their fluorescence spectra are sensitive to the physical state of the surrounding phospholipids. In membranes, prodan appears to localize at the surface, although Fourier transform infrared […]

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N,N-Dimethyl-6-propionyl-2-naphthylamine 500 mg  | >98%

AdipoGen Life Sciences

N,N-dimethyl-6-propionyl-2-naphthylamine (prodan) has both an electron-donor and an electron-acceptor substituent, resulting in a large excited-state dipole moment and extensive solvent polarity-dependent fluorescence shifts. When prodan is incorporated into membranes, their fluorescence spectra are sensitive to the physical state of the surrounding phospholipids. In membranes, prodan appears to localize at the surface, although Fourier transform infrared […]

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N4-Acetylsulfadimethoxine 25 mg  | >98%

AdipoGen Life Sciences

Metabolite of the long-acting sulfonamide antibiotic sulfadimethoxine, used in freshwater aquaculture. Sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a 4,6-dimethoxy-pyrimidin-2-yl group at the nitrogen atom. Compound can be used as analytical reference material.

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N4-Acetylsulfadimethoxine 100 mg  | >98%

AdipoGen Life Sciences

Metabolite of the long-acting sulfonamide antibiotic sulfadimethoxine, used in freshwater aquaculture. Sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a 4,6-dimethoxy-pyrimidin-2-yl group at the nitrogen atom. Compound can be used as analytical reference material.

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N4-Acetylsulfamethoxazole 10 mg  | >99%

AdipoGen Life Sciences

This is a metabolite of the sulfonamide bacteriostatic antibiotic sulfamethoxazole. Sulfamethoxazole is metabolized via acetylation, catalyzed by liver extramitochondrial N-acetyl transferases. Acetyl-Sulfamethoxazole is excreted in urine. Both compounds can be used as a probe for the molecular percentage enrichement of liver extramitochondrial acetyl-CoA. Acetyl-Sulfamethoxazole can also be used as a reference for sulfamethoxazole impurity and […]

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N4-Acetylsulfamethoxazole 50 mg  | >99%

AdipoGen Life Sciences

This is a metabolite of the sulfonamide bacteriostatic antibiotic sulfamethoxazole. Sulfamethoxazole is metabolized via acetylation, catalyzed by liver extramitochondrial N-acetyl transferases. Acetyl-Sulfamethoxazole is excreted in urine. Both compounds can be used as a probe for the molecular percentage enrichement of liver extramitochondrial acetyl-CoA. Acetyl-Sulfamethoxazole can also be used as a reference for sulfamethoxazole impurity and […]

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Naphthol AS-E phosphate 500 mg  | >99%

AdipoGen Life Sciences

Histochemical substrate for alkaline phosphatases. Aldolase inhibitor. Small molecule inhibitor. Anticancer compound that directly targets the KIX domain of CBP, resulting in a disrupted CREB-CBP complex, inhibited CREB-target gene induction and inhibited IL-1beta-mediated angiogenic activity in cancer cell lines. Inhibits activity of transcription factor Myb by blocking interaction with KIX domain of coactivator p300 in […]

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Naphthol AS-E phosphate 1 g  | >99%

AdipoGen Life Sciences

Histochemical substrate for alkaline phosphatases. Aldolase inhibitor. Small molecule inhibitor. Anticancer compound that directly targets the KIX domain of CBP, resulting in a disrupted CREB-CBP complex, inhibited CREB-target gene induction and inhibited IL-1beta-mediated angiogenic activity in cancer cell lines. Inhibits activity of transcription factor Myb by blocking interaction with KIX domain of coactivator p300 in […]

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Nargenicin A1 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic against Gram-positive bacteria, particularly Staphylococcus and Clostridia. More effective against multi-resistant strains (MRSA) than erythromycin and vancomycin. Inhibits cell proliferation and induces HL-60 cell differentiation in combination with 1,25-Dihydroxyvitamin-D3 and ATRA. Displays low cytotoxicity compared to erythromycin and spiramycin.

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Nargenicin A1 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic against Gram-positive bacteria, particularly Staphylococcus and Clostridia. More effective against multi-resistant strains (MRSA) than erythromycin and vancomycin. Inhibits cell proliferation and induces HL-60 cell differentiation in combination with 1,25-Dihydroxyvitamin-D3 and ATRA. Displays low cytotoxicity compared to erythromycin and spiramycin.

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NBD-Cl 1 g  | >98%

AdipoGen Life Sciences

NBD chloride is nonfluorescent until it reacts with primary or secondary amines to produce a fluorescent product. NBD chloride has been extensively used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines.

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NBD-Cl 10 g  | >98%

AdipoGen Life Sciences

NBD chloride is nonfluorescent until it reacts with primary or secondary amines to produce a fluorescent product. NBD chloride has been extensively used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines.

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NBD-Cl 50 g  | >98%

AdipoGen Life Sciences

NBD chloride is nonfluorescent until it reacts with primary or secondary amines to produce a fluorescent product. NBD chloride has been extensively used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines.

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NBD-dodecanoic acid 100 mg  | >98%

AdipoGen Life Sciences

Suitable for probing the ligand binding sites of fatty acid and sterol carrier proteins as well as the investigation of lipolysis processes.

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NBD-dodecanoic acid 500 mg  | >98%

AdipoGen Life Sciences

Suitable for probing the ligand binding sites of fatty acid and sterol carrier proteins as well as the investigation of lipolysis processes.

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NBD-F 25 mg  | >98%

AdipoGen Life Sciences

NBD fluoride is similar to NBD chloride except that the former is much more reactive toward amines. Both reagents are nonfluorescent until they react with primary or secondary amines to produce a fluorescent product. NBD chloride and NBD fluoride have been extensively used as derivatizing reagents for chromatography analysis of amino acids and low molecular […]

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NBD-F 250 mg  | >98%

AdipoGen Life Sciences

NBD fluoride is similar to NBD chloride except that the former is much more reactive toward amines. Both reagents are nonfluorescent until they react with primary or secondary amines to produce a fluorescent product. NBD chloride and NBD fluoride have been extensively used as derivatizing reagents for chromatography analysis of amino acids and low molecular […]

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NBD-methylhydrazine 50 mg  | >97%

AdipoGen Life Sciences

N-methyl-4-hydrazino-7-nitrobenzofurezan (MNBDH) is a new reagent for the determination of aldehydes and ketones. MNBDH reacts with carbonyl copmounds in acidic media to the corresponding MNBD-hydrazones. For example formaldehyde hydrazone formed is determined by high-performance liquid chromatography with UV/visible detection at 474 nm. MNBDH has been studied recently as a reagent with reduced interferences by ozone […]

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NBD-methylhydrazine 500 mg  | >97%

AdipoGen Life Sciences

N-methyl-4-hydrazino-7-nitrobenzofurezan (MNBDH) is a new reagent for the determination of aldehydes and ketones. MNBDH reacts with carbonyl copmounds in acidic media to the corresponding MNBD-hydrazones. For example formaldehyde hydrazone formed is determined by high-performance liquid chromatography with UV/visible detection at 474 nm. MNBDH has been studied recently as a reagent with reduced interferences by ozone […]

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NBD-PZ 200 mg  | >99%

AdipoGen Life Sciences

This common fluorescent reagent often used in carbohydrate analysis, is also useful in fluorescence visualization of lysosomes in live cell lines in culture. This fluorophore that has the unusual environmentally sensitive property of increasing fluorescence in low pH environments. Comparison of staining patterns with the common LysoTracker™ or LysoSensor™ dyes indicated comparable staining, albeit using […]

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NBD-PZ 1 g  | >99%

AdipoGen Life Sciences

This common fluorescent reagent often used in carbohydrate analysis, is also useful in fluorescence visualization of lysosomes in live cell lines in culture. This fluorophore that has the unusual environmentally sensitive property of increasing fluorescence in low pH environments. Comparison of staining patterns with the common LysoTracker™ or LysoSensor™ dyes indicated comparable staining, albeit using […]

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NBD-X 200 mg  | >96%

AdipoGen Life Sciences

Fluorescent probe used for investigation of binding sites of fatty acid and sterol carrier proteins, also used for cell membrane staining.

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NBD-X 1 g  | >96%

AdipoGen Life Sciences

Fluorescent probe used for investigation of binding sites of fatty acid and sterol carrier proteins, also used for cell membrane staining.

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Nebularine (high purity) 500 µg  | >98%

AdipoGen Life Sciences

Nucleoside analog. Cytotoxic. DNA, RNA and protein synthesis inhibitor. Shows anticancer activity. Anti-mycobacterial. Has tuberculostatic activity. Antifungal activity. Antiviral (anti-Herpes). Adenosine deaminase inhibitor. Can be used to analyze structure determinants of DNA that are recognized by DNA repair enzymes, to locate triple helices at G-C sequences or as an universal base, which can bind to […]

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Nebularine (high purity) 1 mg  | >98%

AdipoGen Life Sciences

Nucleoside analog. Cytotoxic. DNA, RNA and protein synthesis inhibitor. Shows anticancer activity. Anti-mycobacterial. Has tuberculostatic activity. Antifungal activity. Antiviral (anti-Herpes). Adenosine deaminase inhibitor. Can be used to analyze structure determinants of DNA that are recognized by DNA repair enzymes, to locate triple helices at G-C sequences or as an universal base, which can bind to […]

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Necrostatin-1 5 mg  | >98%

AdipoGen Life Sciences

Competitive indoleamine 2,3-dioxygenase (IDO) inhibitor. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor. Showed neuroprotection in a murine model of ischemic brain injury in vivo. Selective and ATP-competitive receptor-interacting protein kinase 1 (RIPK1) inhibitor. Used in inflammatory and degenerative disease models to target RIPK1. Suppresses autophagy and apoptosis in […]

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Necrostatin-1 25 mg  | >98%

AdipoGen Life Sciences

Competitive indoleamine 2,3-dioxygenase (IDO) inhibitor. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor. Showed neuroprotection in a murine model of ischemic brain injury in vivo. Selective and ATP-competitive receptor-interacting protein kinase 1 (RIPK1) inhibitor. Used in inflammatory and degenerative disease models to target RIPK1. Suppresses autophagy and apoptosis in […]

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Neobavaisoflavone 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial and antifungal compound. Displays antibiotic activity against Gram-negative multidrug resistant bacteria. Anticancer compound. DNA polymerase inhibitor. Enhances TRAIL-induced apoptosis via inhibition of metastasis. Anti-inflammatory agent inhibiting IL-6-induced STAT3 activation and phosphorylation. Platelet aggregation inhibitor. Human carboxylesterase 1&2 and UDP-glucuronosyltransferase 1A1 inhibitor, enzymes important in drug metabolism. Antioxidant. Inhibits the production of nitric oxide […]

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Neoxaline 1 mg  | >97%

AdipoGen Life Sciences

Antimitotic. Cell cycle inhibitor at the G2/M phase. Antiproliferative. Weak CNS stimulant with weak inhibitory activity on blood platelet aggregation. Mycotoxin.

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