AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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HCPI 50 mg  | >90%

AdipoGen Life Sciences

2-(4-Hydrazinocarbonylphenyl)-4,5-diphenylimidazole (HCPI) as a lophine derivative is a versatile fluorescent derivatization reagent for fatty acids. HCPI has a hydrazinocarbonyl group which reacts with fatty acids resulting in intensely fluorescent derivatives.

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HCPI 250 mg  | >90%

AdipoGen Life Sciences

2-(4-Hydrazinocarbonylphenyl)-4,5-diphenylimidazole (HCPI) as a lophine derivative is a versatile fluorescent derivatization reagent for fatty acids. HCPI has a hydrazinocarbonyl group which reacts with fatty acids resulting in intensely fluorescent derivatives.

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Helenalin 500 µg  | >97%

AdipoGen Life Sciences

Anticancer compound. NF-kappaB inhibitor. Apoptosis inducer. Potent anti-inflammatory agent. Telomerase inhibitor. Anti-trypanosomal and antiprotozoal compound Antibiotic. Shows anti-proliferative effects in 3T3-L1 preadipocytes. Autophagy inducer.

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Heliquinomycin 250 µg  | >80%

AdipoGen Life Sciences

Antibiotic. DNA helicase inhibitor. Inhibits the DNA helicase activity of the human minichromosome maintenance (MCM) 4/6/7 complex. Topoisomerase I and II inhibitor (weaker than DNA helicase). DNA and RNA synthesis inhibitor in cell culture. Does not inhibit protein synthesis. Induces cell cycle arrest. Anticancer compound. Antibacterial against Gram-positive bacteria.

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Heliquinomycin 500 µg  | >80%

AdipoGen Life Sciences

Antibiotic. DNA helicase inhibitor. Inhibits the DNA helicase activity of the human minichromosome maintenance (MCM) 4/6/7 complex. Topoisomerase I and II inhibitor (weaker than DNA helicase). DNA and RNA synthesis inhibitor in cell culture. Does not inhibit protein synthesis. Induces cell cycle arrest. Anticancer compound. Antibacterial against Gram-positive bacteria.

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Hellebrin 1 mg  | >99%

AdipoGen Life Sciences

Highly potent Na+/K+-ATPase inhibitor, blocking the active efflux of Na+ and reuptake of K+. Water soluble cardiotonic glycoside from the class of bufadienolides (with 2-pyrone ring). Inhibits cancer cell growth in vitro. Shown to induce caspase-dependent apoptosis, reducing MDR resistance and the rate of mitochondrial oxidative phosphorylation in cancer cells. Inotropic by increasing the intracellular […]

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Hellebrin 5 mg  | >99%

AdipoGen Life Sciences

Highly potent Na+/K+-ATPase inhibitor, blocking the active efflux of Na+ and reuptake of K+. Water soluble cardiotonic glycoside from the class of bufadienolides (with 2-pyrone ring). Inhibits cancer cell growth in vitro. Shown to induce caspase-dependent apoptosis, reducing MDR resistance and the rate of mitochondrial oxidative phosphorylation in cancer cells. Inotropic by increasing the intracellular […]

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Helvolic acid 1 mg  | >96%

AdipoGen Life Sciences

Steroidal triterpene. Antibiotic. Antibacterial. Shows broad activity against Gram positive and negative bacteria. Mycotoxin. Antifungal. Oxidized LDL uptake inhibitor. Phytotoxin. Inhibitor of the protein biosynthesis through archeal elongation factor 2 (EF-2).

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Helvolic acid 5 mg  | >96%

AdipoGen Life Sciences

Steroidal triterpene. Antibiotic. Antibacterial. Shows broad activity against Gram positive and negative bacteria. Mycotoxin. Antifungal. Oxidized LDL uptake inhibitor. Phytotoxin. Inhibitor of the protein biosynthesis through archeal elongation factor 2 (EF-2).

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Heptelidic acid 250 µg  | >95%

AdipoGen Life Sciences

Antibiotic. Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH. Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Antimalarial. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase […]

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Heptelidic acid 1 mg  | >95%

AdipoGen Life Sciences

Antibiotic. Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH. Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Antimalarial. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase […]

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Heptenophos 100 mg  | >98%

AdipoGen Life Sciences

Synthetic insecticides derived from phosphoric acid, and capable of disrupting neurotransmission in insects and vertebrates. Ectoparasitocidal drug that works as an acetylcholine esterase inhibitor in arthropods. Compound can be used as analytical reference material.

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Heptenophos 500 mg  | >98%

AdipoGen Life Sciences

Synthetic insecticides derived from phosphoric acid, and capable of disrupting neurotransmission in insects and vertebrates. Ectoparasitocidal drug that works as an acetylcholine esterase inhibitor in arthropods. Compound can be used as analytical reference material.

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Herbimycin A 100 µg  | >99%

AdipoGen Life Sciences

Benzoquinone ansamycin antibiotic. Herbicidal compound. Potent, selective, irreversible and cell permeable protein tyrosine kinase inhibitor. Inhibitor of v-Src, Yes, Fps, Ros, Bcr-Abl and ErbB oncogene products. Antitumor compound. Antiangiogenic. Inhibits NF-kappaB activation and phosphorylation of phospholipase C-gamma1. Inhibitor of heat shock protein 90 (Hsp90). Binds Hsp90 and destabilizes client proteins leading to their ubiquitination and […]

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Herbimycin A 1 mg  | >99%

AdipoGen Life Sciences

Benzoquinone ansamycin antibiotic. Herbicidal compound. Potent, selective, irreversible and cell permeable protein tyrosine kinase inhibitor. Inhibitor of v-Src, Yes, Fps, Ros, Bcr-Abl and ErbB oncogene products. Antitumor compound. Antiangiogenic. Inhibits NF-kappaB activation and phosphorylation of phospholipase C-gamma1. Inhibitor of heat shock protein 90 (Hsp90). Binds Hsp90 and destabilizes client proteins leading to their ubiquitination and […]

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Hoechst 33258 500 mg  | >98%

AdipoGen Life Sciences

Useful for staining DNA, chromosomes and nuclei. Binds to the minor groove of DNA at AT-rich sequences. This dye is commonly used for determining the DNA content of viable cells without detergent treatment or fixation and for fluorescence microscopy or flow cytometry.

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Hoechst 33258 5 g  | >98%

AdipoGen Life Sciences

Useful for staining DNA, chromosomes and nuclei. Binds to the minor groove of DNA at AT-rich sequences. This dye is commonly used for determining the DNA content of viable cells without detergent treatment or fixation and for fluorescence microscopy or flow cytometry.

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Hoechst 33342 25 mg  | >98%

AdipoGen Life Sciences

Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry. Suitable for vital DNA staining of a variety of cell types and as a probe of membrane permeability in mammalian cells.

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Hoechst 33342 500 mg  | >98%

AdipoGen Life Sciences

Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry. Suitable for vital DNA staining of a variety of cell types and as a probe of membrane permeability in mammalian cells.

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Hoechst 33342 5 g  | >98%

AdipoGen Life Sciences

Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry. Suitable for vital DNA staining of a variety of cell types and as a probe of membrane permeability in mammalian cells.

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Hoechst 34580 5 mg  | >98%

AdipoGen Life Sciences

The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy. The blue fluorescent Hoechst dye is a cell permeable nucleic acid stain that has multiple applications, including sensitive detection of DNA in the presence of RNA in agarose gels, automated DNA determination, sensitive determination of cell number and chromosome sorting. […]

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Hoechst 34580 50 mg  | >98%

AdipoGen Life Sciences

The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy. The blue fluorescent Hoechst dye is a cell permeable nucleic acid stain that has multiple applications, including sensitive detection of DNA in the presence of RNA in agarose gels, automated DNA determination, sensitive determination of cell number and chromosome sorting. […]

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Hordenin 1 g  | >97%

AdipoGen Life Sciences

Hordenine is a phenethylamine type alkaloid found naturally in various plants such as barley and cacti. Hordenine may be used as an analytical reference material and in research on the activities of phenethylamine type alkaloids. Quorum-sensing inhibitor (QSI).

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Hordenin 5 g  | >97%

AdipoGen Life Sciences

Hordenine is a phenethylamine type alkaloid found naturally in various plants such as barley and cacti. Hordenine may be used as an analytical reference material and in research on the activities of phenethylamine type alkaloids. Quorum-sensing inhibitor (QSI).

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Hordenin 50 g  | >97%

AdipoGen Life Sciences

Hordenine is a phenethylamine type alkaloid found naturally in various plants such as barley and cacti. Hordenine may be used as an analytical reference material and in research on the activities of phenethylamine type alkaloids. Quorum-sensing inhibitor (QSI).

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Hormaomycin 500 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Peptide lactone. Antibacterial agent (selective). Potent narrow-spectrum antibiotic against coryneform actinomycetes (MIC value 88 pM). Quorum sensing modulator. Shows hormonal activity. Inducer of morphological differentiation in actinomycetes. Stimulator of antibiotic production. Inducer of aerial mycelium formation in various actinomycetes. Antimalarial (in vitro). Rare type of natural product, regulating bacterial behavior and independently function in […]

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Hormaomycin 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Peptide lactone. Antibacterial agent (selective). Potent narrow-spectrum antibiotic against coryneform actinomycetes (MIC value 88 pM). Quorum sensing modulator. Shows hormonal activity. Inducer of morphological differentiation in actinomycetes. Stimulator of antibiotic production. Inducer of aerial mycelium formation in various actinomycetes. Antimalarial (in vitro). Rare type of natural product, regulating bacterial behavior and independently function in […]

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HPTS 1 g  | >98%

AdipoGen Life Sciences

Useful for optical sensor applications. Fluorescent pH indicator for physiological range.

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HPTS 5 g  | >98%

AdipoGen Life Sciences

Useful for optical sensor applications. Fluorescent pH indicator for physiological range.

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HPTS 10 g  | >98%

AdipoGen Life Sciences

Useful for optical sensor applications. Fluorescent pH indicator for physiological range.

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Hurghadolide A 10 µg  | >98%

AdipoGen Life Sciences

Cell permeable dilactone macrolide. Potent cytotoxic compound against selected cancer cells. Depolymerizes actin filaments (F-actin). Potent disruptor of cellular microfilaments. Antifungal against Candida albicans.

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Hydramethylnon 100 mg  | >98%

AdipoGen Life Sciences

Insecticide primarily used against cockroaches and ants. Chemical class called trifluoromethyl aminohydrazone, which is a metabolic inhibitor. It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation. Compound can be used as analytical reference material.

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Hydramethylnon 1 g  | >98%

AdipoGen Life Sciences

Insecticide primarily used against cockroaches and ants. Chemical class called trifluoromethyl aminohydrazone, which is a metabolic inhibitor. It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation. Compound can be used as analytical reference material.

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Hymenidin 1 mg  | >97%

AdipoGen Life Sciences

Inhibitor of CDK5/p25 (IC50=4µM) and GSK-3beta (IC50=12µM). Potentially useful in neuronal diseases research. Antagonist of serotonergic receptors. Shown to reduce voltage-dependent calcium elevation. Moderate anticancer compound. Inhibits cell growth in a panel of cancer cell lines at low µM range. Antiprotozoal agent. Antibacterial. Plays a role in the sponge antibacterial defense.

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Hyperforin . DCHA 500 µg  | >97%

AdipoGen Life Sciences

Key constituent of St. John’s wort. Shows properties of potential pharmacological interest, including antibacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Activator of the pregnane X receptor (PXR). Regulates expression of the cytochrome P450 CYP3A4 […]

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Hyperforin . DCHA 1 mg  | >97%

AdipoGen Life Sciences

Key constituent of St. John’s wort. Shows properties of potential pharmacological interest, including antibacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Activator of the pregnane X receptor (PXR). Regulates expression of the cytochrome P450 CYP3A4 […]

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Hypericin 1 mg  | >98%

AdipoGen Life Sciences

One of the principal active constituents of St. John’s Wort (Hypericum perforatum). Hypericin is a photosensitive pigment/chromophore with bright red fluorescence emission (lambdamax: 594nm). Has a high triplet quantum yield and ability to produce considerable amounts of singlet oxygen and other ROS species when photoactivated. Antiviral, anticancer and antidepressant agent. Inactivates enveloped viruses (including HIV). […]

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Hypericin 5 mg  | >98%

AdipoGen Life Sciences

One of the principal active constituents of St. John’s Wort (Hypericum perforatum). Hypericin is a photosensitive pigment/chromophore with bright red fluorescence emission (lambdamax: 594nm). Has a high triplet quantum yield and ability to produce considerable amounts of singlet oxygen and other ROS species when photoactivated. Antiviral, anticancer and antidepressant agent. Inactivates enveloped viruses (including HIV). […]

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Hypericin 10 mg  | >98%

AdipoGen Life Sciences

One of the principal active constituents of St. John’s Wort (Hypericum perforatum). Hypericin is a photosensitive pigment/chromophore with bright red fluorescence emission (lambdamax: 594nm). Has a high triplet quantum yield and ability to produce considerable amounts of singlet oxygen and other ROS species when photoactivated. Antiviral, anticancer and antidepressant agent. Inactivates enveloped viruses (including HIV). […]

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Hypothemycin 250 µg  | >98%

AdipoGen Life Sciences

Antifungal. Cytotoxic against some tumor cell lines, partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells. Modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Potent and selective threonine/tyrosine-specific kinase, MEK and other protein kinases inhibitor in both in vitro and in vivo […]

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Hypothemycin 1 mg  | >98%

AdipoGen Life Sciences

Antifungal. Cytotoxic against some tumor cell lines, partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells. Modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Potent and selective threonine/tyrosine-specific kinase, MEK and other protein kinases inhibitor in both in vitro and in vivo […]

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IBMX 500 mg  | >99%

AdipoGen Life Sciences

Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity.

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IBMX 1 g  | >99%

AdipoGen Life Sciences

Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity.

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Ibrutinib 5 mg  | >98%

AdipoGen Life Sciences

Potent and highly selective Bruton’s tyrosine kinase (BTK) inhibitor. Orally bioavailable and irreversible inhibitor of BTK (IC50 = 0.5 nM) with antineoplastic activity. Binds to and irreversibly inhibits BTK activity, preventing B cell activation and B cell-mediated signaling. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. Shown to […]

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Ibrutinib 25 mg  | >98%

AdipoGen Life Sciences

Potent and highly selective Bruton’s tyrosine kinase (BTK) inhibitor. Orally bioavailable and irreversible inhibitor of BTK (IC50 = 0.5 nM) with antineoplastic activity. Binds to and irreversibly inhibits BTK activity, preventing B cell activation and B cell-mediated signaling. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. Shown to […]

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