AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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Dihydroartemisinin 50 mg  | >98%

AdipoGen Life Sciences

Active metabolite of artemisinin. Anti-malaria (Plasmodium). Anti-schistosoma. Apoptosis inducer. Anti-cancer. Anti-inflammatory Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Autophagy inducer.

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Dihydroartemisinin 250 mg  | >98%

AdipoGen Life Sciences

Active metabolite of artemisinin. Anti-malaria (Plasmodium). Anti-schistosoma. Apoptosis inducer. Anti-cancer. Anti-inflammatory Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Autophagy inducer.

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Dihydroartemisinin 1 g  | >98%

AdipoGen Life Sciences

Active metabolite of artemisinin. Anti-malaria (Plasmodium). Anti-schistosoma. Apoptosis inducer. Anti-cancer. Anti-inflammatory Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Autophagy inducer.

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Dihydrocapsiate 10 mg  | >98%

AdipoGen Life Sciences

Structurally related to capsaicin and found in the non-pungent pepper strain, CH-19 Sweet. Activates the transient receptor potential vanilloid 1 (TRPV1). Shown to have antioxidant, apoptosis incuding in tumor cell lines and anti-inflammatory activities. Inhibited vascular endothelial growth factor (VEGF)-induced proliferation, chemotactic motility, and capillary-like tube formation of primary cultured human endothelial cells. Stimulation of […]

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Dihydrocapsiate 100 mg  | >98%

AdipoGen Life Sciences

Structurally related to capsaicin and found in the non-pungent pepper strain, CH-19 Sweet. Activates the transient receptor potential vanilloid 1 (TRPV1). Shown to have antioxidant, apoptosis incuding in tumor cell lines and anti-inflammatory activities. Inhibited vascular endothelial growth factor (VEGF)-induced proliferation, chemotactic motility, and capillary-like tube formation of primary cultured human endothelial cells. Stimulation of […]

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Dihydrochlamydocin 250 µg  | ≥95%

AdipoGen Life Sciences

Phytotoxin. Derivative of HDAC inhibitor chlamydocin Similar chemical structure to the TAN-1746 compounds (potent HDAC inhibitors).

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Dihydrochlamydocin 1 mg  | >95%

AdipoGen Life Sciences

Phytotoxin. Derivative of HDAC inhibitor chlamydocin Similar chemical structure to the TAN-1746 compounds (potent HDAC inhibitors).

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Dihydroethidium 100 mg  | >95%

AdipoGen Life Sciences

Redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.

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Dihydroethidium 1 g  | >95%

AdipoGen Life Sciences

Redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.

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Dihydrofluorescein diacetate 1 g  | >97%

AdipoGen Life Sciences

Dihydrofluorescein diacetate is a fluorescent probe for detecting intracellular oxidants. It is hydrolyzed by cellular esterases to dihydrofluorescein and is then oxidized to fluorescein primarily by H2O2. Dihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Cell-loading studies indicate that dihydrofluorescein achieves higher intracellular […]

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Dihydrofluorescein diacetate 10 g  | >97%

AdipoGen Life Sciences

Dihydrofluorescein diacetate is a fluorescent probe for detecting intracellular oxidants. It is hydrolyzed by cellular esterases to dihydrofluorescein and is then oxidized to fluorescein primarily by H2O2. Dihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Cell-loading studies indicate that dihydrofluorescein achieves higher intracellular […]

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Dihydromanumycin A 1 mg  | >95%

AdipoGen Life Sciences

Derivative of the farnesyltransferase inhibitor Manumycin A (Prod. No. BVT-0091 http://www.adipogen.com/bvt-0091/manumycin-a.html ). This compound has not yet been thoroughly tested for its biological activity.

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Dihydrorhodamine 123 2 mg  | >95%

AdipoGen Life Sciences

Cell-permeable non-fluorescent reactive oxygen species (ROS) indicator. Passively diffuses across membranes where it is oxidized by peroxynitrite to rhodamine 123 which localizes in the mitochondria and exhibits green fluorescence (Ex/Em wavelengths of 500 and 536 nm). Used to investigate reactive oxygen intermediates produced by human and murine phagocytes, activated rat mast cells and cultured endothelial […]

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Dihydrorhodamine 123 10 mg  | >95%

AdipoGen Life Sciences

Cell-permeable non-fluorescent reactive oxygen species (ROS) indicator. Passively diffuses across membranes where it is oxidized by peroxynitrite to rhodamine 123 which localizes in the mitochondria and exhibits green fluorescence (Ex/Em wavelengths of 500 and 536 nm). Used to investigate reactive oxygen intermediates produced by human and murine phagocytes, activated rat mast cells and cultured endothelial […]

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Dihydrorhodamine 123 125 mg  | >95%

AdipoGen Life Sciences

Cell-permeable non-fluorescent reactive oxygen species (ROS) indicator. Passively diffuses across membranes where it is oxidized by peroxynitrite to rhodamine 123 which localizes in the mitochondria and exhibits green fluorescence (Ex/Em wavelengths of 500 and 536 nm). Used to investigate reactive oxygen intermediates produced by human and murine phagocytes, activated rat mast cells and cultured endothelial […]

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Dimethylsulfoniopropionate . HCl 100 mg  | >98%

AdipoGen Life Sciences

Naturally occurring organosulfur compound. Osmolyte, osmoprotectant. Antioxidant. Cryoprotectant. Neuroprotective agent. Neuritogenic. Acts against immune-deficient diseases (e.g. cancer). Important in geochemistry, ecology and algal/plant physiology. Metabolite produced primarily by marine phytoplankton and is the main precursor to the climatically important gas dimethylsulfide (DMS).

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DL-3-Hydroxybutyric acid sodium salt 1 g  | >98%

AdipoGen Life Sciences

Neuroprotective compound in experimental models of neurodegenerative diseases. Shown to be oxidized as an energetic substrate in the brain during starvation. May inhibit brain glucose oxidation, which may account for the suppression of hepatic glucose production observed after administration of ketone bodies in humans.

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DL-3-Hydroxybutyric acid sodium salt 10 g  | >98%

AdipoGen Life Sciences

Neuroprotective compound in experimental models of neurodegenerative diseases. Shown to be oxidized as an energetic substrate in the brain during starvation. May inhibit brain glucose oxidation, which may account for the suppression of hepatic glucose production observed after administration of ketone bodies in humans.

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DL-3-Hydroxyisobutyric acid sodium salt 250 mg  | >96%

AdipoGen Life Sciences

Intermediate formed in the valine catabolism. It is a reactant of the enzymes involved in branched chain amino acid metabolism 3-hydroxyisobutyrate dehydrogenase and 3-hydroxyisobutyryl-CoA hydrolase and it was found to have increased concentrations in MS patient metabolic profiles. This compound may be used to study the distribution, characterization and kinetics of these enzymes. Shown to […]

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DL-3-Hydroxyisobutyric acid sodium salt 1 g  | >96%

AdipoGen Life Sciences

Intermediate formed in the valine catabolism. It is a reactant of the enzymes involved in branched chain amino acid metabolism 3-hydroxyisobutyrate dehydrogenase and 3-hydroxyisobutyryl-CoA hydrolase and it was found to have increased concentrations in MS patient metabolic profiles. This compound may be used to study the distribution, characterization and kinetics of these enzymes. Shown to […]

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DMAPB 1 mg  | >95%

AdipoGen Life Sciences

Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =114nM). Displays selectivity over other HDACs (IC50=1-8µM). Neuroprotective and anti-neuroinflammatory agent. Reduced neuronal degeneration after traumatic brain injury (TBI). Shown to increase histone H3 acetylation. HDAC6 deacetylates tubulin, HSP90 and the core histones (H2A, H2B, H3, H4). Histone deacetylases act via the formation of large […]

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DMAPB 5 mg  | >95%

AdipoGen Life Sciences

Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =114nM). Displays selectivity over other HDACs (IC50=1-8µM). Neuroprotective and anti-neuroinflammatory agent. Reduced neuronal degeneration after traumatic brain injury (TBI). Shown to increase histone H3 acetylation. HDAC6 deacetylates tubulin, HSP90 and the core histones (H2A, H2B, H3, H4). Histone deacetylases act via the formation of large […]

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DMNQ 5 mg  | >99%

AdipoGen Life Sciences

Cell permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Intracellular superoxide anion formation/ROS generation inducer. Anticancer agent. Shown to induce cell proliferation, apoptosis, necrosis and necroptosis in vitro, dependent on concentration, time, temperature and cell type. Valuable tool for the generation of reactive oxygen species (ROS) in order to study the role of ROS in cell […]

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DMNQ 10 mg  | >99%

AdipoGen Life Sciences

Cell permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Intracellular superoxide anion formation/ROS generation inducer. Anticancer agent. Shown to induce cell proliferation, apoptosis, necrosis and necroptosis in vitro, dependent on concentration, time, temperature and cell type. Valuable tool for the generation of reactive oxygen species (ROS) in order to study the role of ROS in cell […]

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DMNQ 25 mg  | >99%

AdipoGen Life Sciences

Cell permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Intracellular superoxide anion formation/ROS generation inducer. Anticancer agent. Shown to induce cell proliferation, apoptosis, necrosis and necroptosis in vitro, dependent on concentration, time, temperature and cell type. Valuable tool for the generation of reactive oxygen species (ROS) in order to study the role of ROS in cell […]

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DMNQ 10 mg  | >99%

AdipoGen Life Sciences

A cell-permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Generates superoxide production and induces cell proliferation, apoptosis and necrosis in vitro. Redox cycling agent.

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DMNQ 50 mg  | >99%

AdipoGen Life Sciences

A cell-permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Generates superoxide production and induces cell proliferation, apoptosis and necrosis in vitro. Redox cycling agent.

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DPM 25 mg  | >97%

AdipoGen Life Sciences

Nonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the nonsubsituted phthalimidyl group. The analytical sensitivity of N-[4-(5,6-Dimethoxy-N-phthalimidyl)phenyl]maleimide (DPM) is about 3-times higher than that of N-[4-(2-phthalimidyl)phenyl]maleimide (PPM). DPM can be used as a precolumn labeling reagent in HPLC. DPM was […]

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DPM 250 mg  | >97%

AdipoGen Life Sciences

Nonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the nonsubsituted phthalimidyl group. The analytical sensitivity of N-[4-(5,6-Dimethoxy-N-phthalimidyl)phenyl]maleimide (DPM) is about 3-times higher than that of N-[4-(2-phthalimidyl)phenyl]maleimide (PPM). DPM can be used as a precolumn labeling reagent in HPLC. DPM was […]

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DPVP (Resveratrol Analog) 1 mg  | >98%

AdipoGen Life Sciences

Anticancer compound. Shown to inhibit progression of prostate cancer cells. Anti-obesity agent. 3T3-L1 adipocyte differentiation and FAS expression inhibitor.

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Ds(+)-threo-Isocitric acid . trisodium salt 25 mg  | >98%

AdipoGen Life Sciences

Anticoagulant that retains platelets functionality. Buffers Ca2+ activity in physiological range (~1mM). Bypasses the metabolic blockade, may permit heme biosynthesis but does not suffice to reverse the iron-restriction response. Stabilizes the iron-sulfur cluster and is predicted to restore aconitase to its ‘high iron’ conformation and thereby dissociates the PKC-associated signaling complexes whose hyperactivation impairs Epo […]

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Ds(+)-threo-Isocitric acid . trisodium salt 100 mg  | >98%

AdipoGen Life Sciences

Anticoagulant that retains platelets functionality. Buffers Ca2+ activity in physiological range (~1mM). Bypasses the metabolic blockade, may permit heme biosynthesis but does not suffice to reverse the iron-restriction response. Stabilizes the iron-sulfur cluster and is predicted to restore aconitase to its ‘high iron’ conformation and thereby dissociates the PKC-associated signaling complexes whose hyperactivation impairs Epo […]

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DSP-1 1 mg  | >98%

AdipoGen Life Sciences

Fluorescent probe for detection of H2S2 and hydrogen polysulfides in aqueous buffers.

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DSP-1 5 mg  | >98%

AdipoGen Life Sciences

Fluorescent probe for detection of H2S2 and hydrogen polysulfides in aqueous buffers.

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DSP-1 10 mg  | >98%

AdipoGen Life Sciences

Fluorescent probe for detection of H2S2 and hydrogen polysulfides in aqueous buffers.

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