AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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8-Hydroxyjulolidine 25 g  | >97%

AdipoGen Life Sciences

An intermediate and starting material for various coumarin syntheses. Used to prepare aminocoumarins via microwave-accelerated Pechmann reaction or as starting material for coumarin C-ribosides.

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8-Methoxypsoralen 5 g  | >95%

AdipoGen Life Sciences

Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). Has more potency than 5-MOP, 5-OH-P, DH-8-MOP and psoralen in inhibiting CYP2B1 (cytochrome P-450 2B1). Completely inhibits the metabolism of nicotine in vitro. Inhibits the metabolism of caffeine. Methoxsalen is a drug with photoactivating properties used to treat psoriasis, eczema, vitiligo and […]

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9-Anthracenecarbaldehyde 5 g  | >99%

AdipoGen Life Sciences

Fluorescent reagents (probe, stain, label) with reactive functional group for chromatography or spectroscopy. Derivatization agent. Used for membrane research, luminescent detection, molecular biology, protein modifications, protein structural analysis and proteomics. Carbohydrate labels for chromatography.

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9-Anthracenecarbaldehyde 500 g  | >99%

AdipoGen Life Sciences

Fluorescent reagents (probe, stain, label) with reactive functional group for chromatography or spectroscopy. Derivatization agent. Used for membrane research, luminescent detection, molecular biology, protein modifications, protein structural analysis and proteomics. Carbohydrate labels for chromatography.

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9-Methylguanine 100 mg  | >98%

AdipoGen Life Sciences

Nucleic acid base useful for synthesis and complex building. Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.

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9-Methylguanine 250 mg  | >98%

AdipoGen Life Sciences

Nucleic acid base useful for synthesis and complex building. Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.

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9-Methylguanine 1 g  | >98%

AdipoGen Life Sciences

Nucleic acid base useful for synthesis and complex building. Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.

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9-Phenyl-3-fluorone 10 g  | >98%

AdipoGen Life Sciences

Labeling and staining agent for selected trace elements/metals, such as iron, copper and mangan and other targets, by forming complexes which show a colored reaction.

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ABD-F 10 mg  | >98%

AdipoGen Life Sciences

Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC. ABD-F also reportedly reacts slowly with the hydroxy group of some tyrosine residues as well as amino groups […]

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Ac-Arg-Leu-Arg-AMC 1 mg  | >97%

AdipoGen Life Sciences

Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Shows low Km and high specific activity. Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.

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Ac-Arg-Leu-Arg-AMC 5 mg  | >97%

AdipoGen Life Sciences

Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Shows low Km and high specific activity. Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.

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Acetomycin 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial, antifungal and antiprotozoal. Cytotoxic against several tumor cell lines in vitro.

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Acetomycin 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial, antifungal and antiprotozoal. Cytotoxic against several tumor cell lines in vitro.

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Actinomycin D 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antitumor compound. Cytotoxic. Apoptosis inducer. RNA synthesis inhibitor. DNA intercalating agent. Mcl-1 expression inhibitor p53 pathway activator.

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Actinomycin D 25 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antitumor compound. Cytotoxic. Apoptosis inducer. RNA synthesis inhibitor. DNA intercalating agent. Mcl-1 expression inhibitor p53 pathway activator.

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Actinomycin D 100 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antitumor compound. Cytotoxic. Apoptosis inducer. RNA synthesis inhibitor. DNA intercalating agent. Mcl-1 expression inhibitor p53 pathway activator.

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Actinomycin D 20 mg  | >95%

AdipoGen Life Sciences

Biochemical/physiological actions: An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions […]

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Actinomycin X2 1 mg  | >98%

AdipoGen Life Sciences

Aniso-Actinomycin (4-Oxopro instead of Pro in the beta-chain). Antitumor and antiviral antibiotic. Antituberculosis agent. Has higher cytotoxicity towards cultured human leukemia (HL-60) cells than actinomycin D. Apoptosis inducer. Forms a complex with DNA and blocks its biological activity.

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Actinomycin X2 5 mg  | >98%

AdipoGen Life Sciences

Aniso-Actinomycin (4-Oxopro instead of Pro in the beta-chain). Antitumor and antiviral antibiotic. Antituberculosis agent. Has higher cytotoxicity towards cultured human leukemia (HL-60) cells than actinomycin D. Apoptosis inducer. Forms a complex with DNA and blocks its biological activity.

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Actinonin 5 mg  | >97%

AdipoGen Life Sciences

Antibiotic. Aminopeptidase M, N and leucine and alanine aminopeptidase inhibitor. Potent peptide deformylase (PDF) inhibitor. Inhibits MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13, but not MMP-14. Anticancer compound. Antiproliferative. Shows antitumor activity in vitro and in vivo Apoptosis inducer. Meprin A inhibitor.

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Actinonin 25 mg  | >97%

AdipoGen Life Sciences

Antibiotic. Aminopeptidase M, N and leucine and alanine aminopeptidase inhibitor. Potent peptide deformylase (PDF) inhibitor. Inhibits MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13, but not MMP-14. Anticancer compound. Antiproliferative. Shows antitumor activity in vitro and in vivo Apoptosis inducer. Meprin A inhibitor.

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ACY-775 1 mg  | >95%

AdipoGen Life Sciences

Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =7.5nM). Displays high selectivity over HDAC1-9 (IC50=1-10µM). Shows improved brain bioavailability compared to tubastatin A (Prod. No. AG-CR1-3900). Induces hyperacetylation of alpha-tubulin in brain without concurrently altering the acetylation of histones. Shows antidepressant activity. HDAC6 deacetylates tubulin, HSP90 and the core histones (H2A, H2B, H3, […]

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ACY-775 5 mg  | >95%

AdipoGen Life Sciences

Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =7.5nM). Displays high selectivity over HDAC1-9 (IC50=1-10µM). Shows improved brain bioavailability compared to tubastatin A (Prod. No. AG-CR1-3900). Induces hyperacetylation of alpha-tubulin in brain without concurrently altering the acetylation of histones. Shows antidepressant activity. HDAC6 deacetylates tubulin, HSP90 and the core histones (H2A, H2B, H3, […]

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AdipoRon 10 mg  | >98%

AdipoGen Life Sciences

Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5′-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by […]

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AdipoRon 50 mg  | >98%

AdipoGen Life Sciences

Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5′-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by […]

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AdipoRon . hydrochloride (water soluble) 10 mg  | >98%

AdipoGen Life Sciences

Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5′-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by […]

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AdipoRon . hydrochloride (water soluble) 50 mg  | >98%

AdipoGen Life Sciences

Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5′-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by […]

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AEBSF . hydrochloride 50 mg  | >98%

AdipoGen Life Sciences

Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF. Potent, selective inhibitor of Site-1-protease (S1P). Used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation by selectively inhibiting S1P. NAD(P)H oxidase inhibitor. Inhibits activation of TGFbeta and activates JNK and p38 MAP […]

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AEBSF . hydrochloride 250 mg  | >98%

AdipoGen Life Sciences

Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF. Potent, selective inhibitor of Site-1-protease (S1P). Used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation by selectively inhibiting S1P. NAD(P)H oxidase inhibitor. Inhibits activation of TGFbeta and activates JNK and p38 MAP […]

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AEBSF . hydrochloride 1 g  | >98%

AdipoGen Life Sciences

Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF. Potent, selective inhibitor of Site-1-protease (S1P). Used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation by selectively inhibiting S1P. NAD(P)H oxidase inhibitor. Inhibits activation of TGFbeta and activates JNK and p38 MAP […]

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AFC Standard Solution 100 µl  | Purity Not Available

AdipoGen Life Sciences

A fluorogenic standard useful for quantitating assays monitoring 7-amino-4-trifluoromethylcoumarin (AFC) release such as those utilizing ubiquitin-AFC. The concentration of the AFC released can be calculated from a standard curve prepared with AFC standards.

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Aftin-4 1 mg  | >98%

AdipoGen Life Sciences

Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer’s Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly […]

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Aftin-4 5 mg  | >98%

AdipoGen Life Sciences

Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer’s Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly […]

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Aftin-4 25 mg  | >98%

AdipoGen Life Sciences

Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer’s Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly […]

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Aftin-5 1 mg  | >98%

AdipoGen Life Sciences

Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer’s Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly […]

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Aftin-5 5 mg  | >98%

AdipoGen Life Sciences

Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer’s Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly […]

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Aftin-5 25 mg  | >98%

AdipoGen Life Sciences

Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer’s Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly […]

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Ageladine A . TFA 200 µg  | >98%

AdipoGen Life Sciences

Non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, vesicles, cells, tissue and even small whole animals over several days without side effects. Stronger fluorescent intensity under acidic conditions and barely detectable in alkaline solutions (wide range from pH 4 to pH 8). Highly cell/membrane permeable. Trapped within the […]

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