AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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5(6)-ROX N-succinimidyl ester 500 mg  | >95%

AdipoGen Life Sciences

5-(and-6)-Carboxy-X-rhodamine, succinimidyl ester is an amine-reactive long wavelength rhodamine dye. Derivatives made with the amine-reactive carboxy-X-rhodamine (ROX), succinimidyl ester are widely used for oligonucleotide labeling and automated DNA sequencing applications. Conjugates of this dye have longer-wavelength spectra than the spectra of Lissamine rhodamine B conjugates, but somewhat shorter-wavelength spectra than those of Texas Red® conjugates.

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5(6)-TAMRA 100 mg  | >96%

AdipoGen Life Sciences

Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide […]

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5(6)-TAMRA 2 g  | >96%

AdipoGen Life Sciences

Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide […]

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6-(4-Acetamido-1,8-naphthalamido) hexanoic acid 10 mg  | >95%

AdipoGen Life Sciences

The highly fluorescent label 4-acetylamino-1,8-naphthalimide-N-caproic acid has two fused benzene rings containing a closed anhydride ring and therefore is a flat and planar molecule which can easily intercalate or act as a groove binder with DNA/RNA sequences. For the study of in situ hydridization with complementary synthetic oligonucleotides (ODNs), tagging with non-radioactive labels has gained […]

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6-(4-Acetamido-1,8-naphthalamido) hexanoic acid 50 mg  | >95%

AdipoGen Life Sciences

The highly fluorescent label 4-acetylamino-1,8-naphthalimide-N-caproic acid has two fused benzene rings containing a closed anhydride ring and therefore is a flat and planar molecule which can easily intercalate or act as a groove binder with DNA/RNA sequences. For the study of in situ hydridization with complementary synthetic oligonucleotides (ODNs), tagging with non-radioactive labels has gained […]

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6-(Dimethylamino)purine 1 g  | >97%

AdipoGen Life Sciences

A puromycin analog that acts as a protein kinase inhibitor. Selectively induces premature mitosis in mammalian cells. Inhibits TNF-alpha upregulation of ICAM-1, lipolysis, and the activation of JNK/SAPK. Inhibits p34cdc2/cyclin B (IC50 = 300 µM). Induces apoptosis in S-phase-arrested HeLa cells (~5 mM).

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6-(Fluorescein-5(6)-carboxamido)hexanoicacid N-succinimidyl ester 5 mg  | >75%

AdipoGen Life Sciences

Amine-reactive fluorescent probe for introducing a fluorescein label at a nucleophilic residue of a target molecule. This fluorescein labeling reagent has an added (X) spacer to improve accessibility of the reactive group by nucleophiles in preparation of bioconjugates. The reactive N-hydroxysuccinimide (NHS) group can be used for easy attachment to proteins or amine containing nucleotides […]

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6-(Fluorescein-5(6)-carboxamido)hexanoicacid N-succinimidyl ester 25 mg  | >75%

AdipoGen Life Sciences

Amine-reactive fluorescent probe for introducing a fluorescein label at a nucleophilic residue of a target molecule. This fluorescein labeling reagent has an added (X) spacer to improve accessibility of the reactive group by nucleophiles in preparation of bioconjugates. The reactive N-hydroxysuccinimide (NHS) group can be used for easy attachment to proteins or amine containing nucleotides […]

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6-Amino-8-trifluoromethylphenanthridine 1 mg  | >99%

AdipoGen Life Sciences

Potent antiprion agent. Higher activity than 6-Aminophenanthridine (Prod. No. MC-C0029). Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.

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6-Amino-8-trifluoromethylphenanthridine 5 mg  | >99%

AdipoGen Life Sciences

Potent antiprion agent. Higher activity than 6-Aminophenanthridine (Prod. No. MC-C0029). Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.

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6-Amino-8-trifluoromethylphenanthridine 25 mg  | >99%

AdipoGen Life Sciences

Potent antiprion agent. Higher activity than 6-Aminophenanthridine (Prod. No. MC-C0029). Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.

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6-Amino-D-luciferin 1 mg  | >99%

AdipoGen Life Sciences

Amino analog of the common D-luciferin substrate for use in measuring firefly luciferase activity. This cell permeable reagent can be used when considering design of proluminescent bioconjugates (peptidase substrates) of luciferin for ultrasensitive luminescent assays. In bioluminescent protease assays peptides or amino acids are conjugated to the luciferin analog 6-amino-D-luciferin. These substrates are useful for […]

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6-Amino-D-luciferin 5 mg  | >99%

AdipoGen Life Sciences

Amino analog of the common D-luciferin substrate for use in measuring firefly luciferase activity. This cell permeable reagent can be used when considering design of proluminescent bioconjugates (peptidase substrates) of luciferin for ultrasensitive luminescent assays. In bioluminescent protease assays peptides or amino acids are conjugated to the luciferin analog 6-amino-D-luciferin. These substrates are useful for […]

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6-Aminophenanthridine 1 mg  | >97%

AdipoGen Life Sciences

Antiprion agent. Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.

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6-Aminophenanthridine 5 mg  | >97%

AdipoGen Life Sciences

Antiprion agent. Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.

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6-Aminophenanthridine 25 mg  | >97%

AdipoGen Life Sciences

Antiprion agent. Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.

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6-CFDA 25 mg  | >95%

AdipoGen Life Sciences

Used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin. CFDA enter cells and are hydrolysed more slowly than FDA. CFDA and FDA hydrolyses obey Michaelis-Menten kinetics with Km values of around 19 and 2 microM, respectively.

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6-CFDA 100 mg  | >95%

AdipoGen Life Sciences

Used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin. CFDA enter cells and are hydrolysed more slowly than FDA. CFDA and FDA hydrolyses obey Michaelis-Menten kinetics with Km values of around 19 and 2 microM, respectively.

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6-CFDA 1 g  | >95%

AdipoGen Life Sciences

Used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin. CFDA enter cells and are hydrolysed more slowly than FDA. CFDA and FDA hydrolyses obey Michaelis-Menten kinetics with Km values of around 19 and 2 microM, respectively.

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6-CFDA N-succinimidyl ester 5 mg  | >90%

AdipoGen Life Sciences

6-CFDA is membrane-permeant and thus can be loaded into cells via incubation. Once inside the cells, 6-CFDA is hydrolyzed by intracellular esterases to 6-carboxyfluorescein. Reagent for continuously determining the intracellular pH in bacteria by fluorometry. Labeling human intervertebral disk cells in vitro for fluorescence microscopy.

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6-CFDA N-succinimidyl ester 25 mg  | >90%

AdipoGen Life Sciences

6-CFDA is membrane-permeant and thus can be loaded into cells via incubation. Once inside the cells, 6-CFDA is hydrolyzed by intracellular esterases to 6-carboxyfluorescein. Reagent for continuously determining the intracellular pH in bacteria by fluorometry. Labeling human intervertebral disk cells in vitro for fluorescence microscopy.

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6-CFDA N-succinimidyl ester 100 mg  | >90%

AdipoGen Life Sciences

6-CFDA is membrane-permeant and thus can be loaded into cells via incubation. Once inside the cells, 6-CFDA is hydrolyzed by intracellular esterases to 6-carboxyfluorescein. Reagent for continuously determining the intracellular pH in bacteria by fluorometry. Labeling human intervertebral disk cells in vitro for fluorescence microscopy.

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6-ECDCA 5 mg  | >95%

AdipoGen Life Sciences

Potent and selective FXR agonist (EC50= 99nM). Induces SHP in HSCs to suppress TIMP-1 expression. Apoptosis inducer. Protects against liver fibrosis development in rat in vivo. Displays anticholeretic activity in rat in vivo. Promotes preadipocyte differentiation. Regulates adipogenesis and insulin signaling in vivo. Inhibits vascular smooth muscle cell inflammation and migration.

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6-ECDCA 25 mg  | >95%

AdipoGen Life Sciences

Potent and selective FXR agonist (EC50= 99nM). Induces SHP in HSCs to suppress TIMP-1 expression. Apoptosis inducer. Protects against liver fibrosis development in rat in vivo. Displays anticholeretic activity in rat in vivo. Promotes preadipocyte differentiation. Regulates adipogenesis and insulin signaling in vivo. Inhibits vascular smooth muscle cell inflammation and migration.

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6-FAM 50 mg  | >98%

AdipoGen Life Sciences

The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most cells (pH ~6.8-7.4). Carboxyfluorescein is commonly employed as a polar tracer.

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6-FAM 200 mg  | >98%

AdipoGen Life Sciences

The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most cells (pH ~6.8-7.4). Carboxyfluorescein is commonly employed as a polar tracer.

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6-FAM 1 g  | >98%

AdipoGen Life Sciences

The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most cells (pH ~6.8-7.4). Carboxyfluorescein is commonly employed as a polar tracer.

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6-FAM N-succinimidyl ester 10 mg  | >98%

AdipoGen Life Sciences

Popular green fluorescent cell-permeable dye. Covalently couples via its succinimidyl group to intracellular molecules. The amine-reactive succinimidyl ester of 6-FAM acid is a common fluorescent derivatization reagent for covalently labeling peptides, proteins and nucleotides. Due to this covalent coupling reaction it can be retained within cells for extremely long periods and due to this stable […]

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6-FAM N-succinimidyl ester 25 mg  | >98%

AdipoGen Life Sciences

Popular green fluorescent cell-permeable dye. Covalently couples via its succinimidyl group to intracellular molecules. The amine-reactive succinimidyl ester of 6-FAM acid is a common fluorescent derivatization reagent for covalently labeling peptides, proteins and nucleotides. Due to this covalent coupling reaction it can be retained within cells for extremely long periods and due to this stable […]

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6-FAM N-succinimidyl ester 100 mg  | >98%

AdipoGen Life Sciences

Popular green fluorescent cell-permeable dye. Covalently couples via its succinimidyl group to intracellular molecules. The amine-reactive succinimidyl ester of 6-FAM acid is a common fluorescent derivatization reagent for covalently labeling peptides, proteins and nucleotides. Due to this covalent coupling reaction it can be retained within cells for extremely long periods and due to this stable […]

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6-HEX dipivaloate 25 mg  | >98%

AdipoGen Life Sciences

6-HEX is an amino-conjugatable fluorescent probe that is widely used in nucleic acid sequencing and related research. It can also be used to label peptides and oligonucleotides.

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6-HEX dipivaloate 1 g  | >98%

AdipoGen Life Sciences

6-HEX is an amino-conjugatable fluorescent probe that is widely used in nucleic acid sequencing and related research. It can also be used to label peptides and oligonucleotides.

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6-ROX 25 mg  | >90%

AdipoGen Life Sciences

This pure-6 isomer is a derivative of carboxy-X-rhodamine, widely used for oligonucleotide labeling and automated DNA sequencing applications.

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6-ROX 125 mg  | >90%

AdipoGen Life Sciences

This pure-6 isomer is a derivative of carboxy-X-rhodamine, widely used for oligonucleotide labeling and automated DNA sequencing applications.

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6-TAMRA 25 mg  | >90%

AdipoGen Life Sciences

Free acid form of 6-carboxytetramethylrhodamine single isomer. The corresponding succinimidyl ester is a single isomer fluorophore most commonly used in automated DNA sequencing.

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6-TAMRA 250 mg  | >90%

AdipoGen Life Sciences

Free acid form of 6-carboxytetramethylrhodamine single isomer. The corresponding succinimidyl ester is a single isomer fluorophore most commonly used in automated DNA sequencing.

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6-TAMRA N-succinimidyl ester 5 mg  | >97%

AdipoGen Life Sciences

Amine-reactive form of 6-carboxytetramethylrhodamine single isomer used for labeling of peptides and aminoglycoside antibiotics. It is also most commonly used in automated DNA sequencing.

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6-TAMRA N-succinimidyl ester 25 mg  | >97%

AdipoGen Life Sciences

Amine-reactive form of 6-carboxytetramethylrhodamine single isomer used for labeling of peptides and aminoglycoside antibiotics. It is also most commonly used in automated DNA sequencing.

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6-TET dipivaloate 500 mg  | >98%

AdipoGen Life Sciences

6-TET is an amino-conjugatable fluorescent probe that is widely used in nucleic acid sequencing and related research. It can also be used to label peptides and oligonucleotides.

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