1. Conversion of Atrial Fibrillation/Flutter
In patients with symptomatic atrial fibrillation/flutter whose symptoms are not adequately controlled by measures that reduce the rate of ventricular response, quinidine sulfate is indicated as a means of restoring normal sinus rhythm. If this use of quinidine sulfate does not restore sinus rhythm within a reasonable time, then quinidine sulfate should be discontinued.
2. Reduction of Frequency of Relapse Into Atrial Fibrillation/Flutter
Chronic therapy with quinidine sulfate is indicated for some patients at high risk of symptomatic atrial fibrillation/flutter, generally patients who have had previous episodes of atrial fibrillation/flutter that were so frequent and poorly tolerated as to outweigh, in the judgement of the physician and the patient, the risks of prophylactic therapy with quinidine sulfate.
3. Suppression of Ventricular Arrhythmias
Quinidine sulfate is also indicated for the suppression of recurrent documented ventricular arrhythmias, such as sustained ventricular tachycardia, that in the judgement of the physician are lifethreatening.
4. Treatment of Malaria
Quinidine sulfate is also indicated in the treatment of life-threatening Plasmodium falciparum malaria.