Hepatocyte growth factor (HGF) is a potent, mesenchymal-derived mitogen of mature parenchymal hepatocytes and acts as a growth factor for a wide range of tissues and cell types.HGF signals through the transmembrane tyrosine kinase receptor of the MET.The functions of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and the enhancement of neuronal survival.HGF is a Crucial mitogen, especially after partial hepatectomy and other liver injuries.HGF, also known as scattering factor and hepatopoietin A, is a pleiotropic protein in the fibrinogen subfamily of S1 peptidases.