Upadacitinib

Upadacitinib is a JAK inhibitor used for rheumatoid arthritis.

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Catalog Number API0232859
Alternative Name(s) Upadacitinib; ABT-494; Rinvoq
Research Area API
Molecular Formula C17H19F3N6O
CAS# 1310726-60-3
Inchi InChI=1S/C17H19F3N6O/c1-2-10-7-25(16(27)24-9-17(18,19)20)8-11(10)13-5-22-14-6-23-15-12(26(13)14)3-4-21-15/h3-6,10-11,21H,2,7-9H2,1H3,(H,24,27)/t10-,11+/m1/s1
Inchi Key WYQFJHHDOKWSHR-MNOVXSKESA-N
SMILES CC[C@@H]1CN(C[C@@H]1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F
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Upadacitinib

Upadacitinib is an oral selective inhibitor of Janus associated kinase 1 (JAK-1) that is used in the therapy of moderate-to-severe rheumatoid arthritis. Upadacitinib has been associated with a low rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent acute liver injury although it may pose a risk for reactivation of hepatitis B in susceptible patients.

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Catalog Number API1310726603
Alternative Name(s) ABT-494 Rinvoq Upadacitinib anhydrous
Research Area Anti-Gout APIs
Molecular Formula C17H19F3N6O
CAS# 1310726-60-3
SMILES CCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F
Size inquiry
Supplier Page https://www.protheragen.ai/upadacitinib-item-11894.html