Abemaciclib

Abemaciclib is an anticancer drug (CDK4/6 inhibitor).

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Catalog Number	API0232809
Alternative Name(s)	Abemaciclib; 1231929-97-7; Verzenio
Research Area	API
Molecular Formula	C27H32F2N8
CAS#	1231929-97-7
Inchi	InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)
Inchi Key	UZWDCWONPYILKI-UHFFFAOYSA-N
SMILES	CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F
Size	inquiry
Supplier Page	https://apihub.protheragen.ai/abemaciclib-item-1309.html

Abemaciclib is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.

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Catalog Number	API1231929977
Research Area	Active Pharmaceutical Ingredients
Molecular Formula	C27H32F2N8
CAS#	1231929-97-7
Size	inquiry
Supplier Page	https://www.protheragen.ai/abemaciclib-item-6370.html