Pemetrexed

Pemetrexed ditromethamine is an anticancer drug.

Price Not Available inquiry Pemetrexed Supplier Page
Catalog Number API0232683
Alternative Name(s) Pemetrexed; 137281-23-3; CHEBI:63616
Research Area API
Molecular Formula C20H21N5O6
CAS# 137281-23-3
Inchi InChI=1S/C20H21N5O6/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29)/t13-/m0/s1
Inchi Key WBXPDJSOTKVWSJ-ZDUSSCGKSA-N
SMILES C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Size inquiry
Supplier Page https://apihub.protheragen.ai/pemetrexed-item-1183.html

Pemetrexed

Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2′-deoxyuridine-5′-monophosphate (dUMP) to 2′-deoxythymidine-5′-monophosphate (dTMP), an essential precursor in DNA synthesis.

Price Not Available inquiry Pemetrexed Supplier Page
Catalog Number INT137281233
Alternative Name(s) Pemetrexed disodium Alimta LY231514
Research Area Intermediates
Molecular Formula C20H21N5O6
CAS# 137281-23-3
SMILES C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)O)C(=O)O
Size inquiry
Supplier Page https://www.protheragen.ai/pemetrexed-item-12053.html