Estradiol

Estradiol Valerate is an estrogen.

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Catalog Number API0232248
Alternative Name(s) estradiol; Oestradiol; progynon
Research Area API
Molecular Formula C18H24O2
CAS# 50-28-2
Inchi InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
Inchi Key VOXZDWNPVJITMN-ZBRFXRBCSA-N
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O
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β-Estradiol

Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams. When used for oral or IM administration, estradiol is commonly synthesized as a pro-drug ester (such as [DB13952], [DB13953], [DB13954], [DB13955], and [DB13956]). Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs). Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration.

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Catalog Number PIPE-0767
Alternative Name(s) estradiol beta-Estradiol 17beta-Estradiol Oestradiol
Research Area Natural Extract
Molecular Formula C18H24O2
CAS# 50-28-2
SMILES CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
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