Betamethasone Sodium Phosphate

Betamethasone Dipropionate is a topical corticosteroid.

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Catalog Number API0231871
Alternative Name(s) Betamethasone sodium phosphate; 151-73-5; Betamethasone 21-phosphate disodium salt
Research Area API
Molecular Formula C22H28FNa2O8P
CAS# 151-73-5
Inchi InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1
Inchi Key PLCQGRYPOISRTQ-LWCNAHDDSA-L
SMILES C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
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Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate is the disodium salt of the 21-phosphate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone sodium phosphate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

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Catalog Number API151735
Alternative Name(s) Bentelan Betamethasone 21-phosphate disodium salt Betamethasone disodium phosphate
Research Area APIs for Cortisones
Molecular Formula C22H28FNa2O8P
CAS# 151-73-5
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
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