Enzalutamide

Entrectinib is an anticancer drug (TRK inhibitor).

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Catalog Number API0231543
Alternative Name(s) Enzalutamide; 915087-33-1; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide
Research Area API
Molecular Formula C21H16F4N4O2S
CAS# 915087-33-1
Inchi InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)
Inchi Key WXCXUHSOUPDCQV-UHFFFAOYSA-N
SMILES CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NC)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C
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Enzalutamide

Used for the treatment of of metastatic castration-resistant prostate cancer. It has a role as an antineoplastic agent and an androgen antagonist.

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Catalog Number API915087331
Alternative Name(s) MDV3100 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide
Research Area Anti-Tumor APIs
Molecular Formula C21H16F4N4O2S
CAS# 915087-33-1
SMILES CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NC)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C
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