Raleukin
Anakinra (Raleukin, AMG-719) is an exogenous antagonist of recombinant human interleukin-1 receptor that also inhibits caspase-1 and caspase-9 activity with Ki of 0.201 μM and 0.31 μM respectively. It is used in research to study IL-1 blockade in inflammation, tumor growth, islet transplantation, and cardiac injury models.
| Trivial name | AMG-719; Anakinra |
| Catalog Number | P1235 |
| Molecular Formula | C14H18O3 |
| CAS# | 143090-92-0 |
| Inchi | InChI=1S/C14H18O3/c1-14(2,3)13(15)7-5-10-4-6-11-12(8-10)17-9-16-11/h4-8,13,15H,9H2,1-3H3/b7-5+ |
| Inchi Key | IBLNKMRFIPWSOY-FNORWQNLSA-N |
| SMILES | CC(C)(C)C(C=CC1=CC2=C(C=C1)OCO2)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/raleukin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/p1235-raleukin-chemical-structure-tube.png |