YJ9069

YJ9069 is a potent, selective and orally bioavailable PROTAC degrader of CDK12/CDK13. It inhibits proliferation in prostate cancer cells by inducing gene-length-dependent transcriptional elongation defects, leading to DNA damage, cell-cycle arrest, and significant tumor growth suppression in vivo.

Price Not Available 1mg YJ9069 Supplier Page

Catalog Number	E8303
Molecular Formula	C25H24N2O6
Inchi	InChI=1S/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+
Inchi Key	XTFPDGZNWTZCMF-DHZHZOJOSA-N
SMILES	CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC
Size	1mg
Supplier Page	http://www.selleckchem.com/products/yj9069.html
Additional Information	https://file.selleck.cn/downloads/struct/e8303-yj9069-chemical-structure-tube.png