SHP1705
SHP1705 is a potent and selective activator of Cryptochrome 2 (CRY2). It inhibits BMAL1-CLOCK transcriptional activity and significantly enhances efficacy against glioblastoma stem cells (GSCs) and PDX tumors and can be used in research on GSC biology and survival in glioblastoma (GBM).
| Trivial name | KRASG12C IN-13 |
| Catalog Number | E8299 |
| Molecular Formula | C8H18N2O3S |
| CAS# | 1817737-04-4 |
| Inchi | InChI=1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12) |
| Inchi Key | KJQFBVYMGADDTQ-UHFFFAOYSA-N |
| SMILES | CCCCS(=N)(=O)CCC(C(=O)O)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/shp1705.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8299-shp1705-chemical-structure-tube.png |