YD54
YD54 is a potent, selective and orally bioavailable PROTAC and a degrader of SMARCA2 with DC50 of 8.1 nM at 24 hours. It exhibits antitumor activity in SMARCA4-mutant lung cancer xenograft models and can be used in research on non-small cell lung cancer.
| Trivial name | Flezurafenibum |
| Catalog Number | E8293 |
| Molecular Formula | C12H15N3O6 |
| CAS# | 2951015-30-6 |
| Inchi | InChI=1S/C12H15N3O6/c16-10-13(1-7-4-19-7)11(17)15(3-9-6-21-9)12(18)14(10)2-8-5-20-8/h7-9H,1-6H2 |
| Inchi Key | OUPZKGBUJRBPGC-UHFFFAOYSA-N |
| SMILES | C1C(O1)CN2C(=O)N(C(=O)N(C2=O)CC3CO3)CC4CO4 |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/yd54.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8293-yd54-chemical-structure-tube.png |