PM534
PM534 is a potent microtubule-targeting agent (MTA) that binds the colchicine-binding domain (CBD) and inhibits tubulin assembly with IC50 values ranging from 0.8 to 3.2 nM. It also significantly inhibits tumor growth in mouse xenograft models of human non-small cell lung cancer.
| Catalog Number | E8284 |
| Molecular Formula | C15H24N2 |
| CAS# | 2446376-25-4 |
| Inchi | InChI=1S/C15H24N2/c1-2-7-17-10-13-9-12(14(17)5-1)8-11-4-3-6-16-15(11)13/h8,12-16H,1-7,9-10H2/t12-,13+,14+,15+/m0/s1 |
| Inchi Key | SKOLRLSBMUGVOY-GBJTYRQASA-N |
| SMILES | C1CCN2CC3CC(C2C1)C=C4C3NCCC4 |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/pm534.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8284-pm534-chemical-structure-tube.png |