RJG-2051
RJG-2051 is a selective covalent SuTEx inhibitor of AKR1C3 with an IC50 of 13 nM that targets a noncatalytic tyrosine residue (Y24), effectively blocking its enzymatic activity and disrupting androgen, estrogen, and prostaglandin metabolism.
| Catalog Number | E8282 |
| Molecular Formula | C14H19ClN2O2 |
| CAS# | 2851993-77-4 |
| Inchi | InChI=1S/C14H19ClN2O2/c15-13-4-2-12(3-5-13)14(18)16-6-1-7-17-8-10-19-11-9-17/h2-5H,1,6-11H2,(H,16,18) |
| Inchi Key | YYFGRAGNYHYWEZ-UHFFFAOYSA-N |
| SMILES | C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/rjg-2051.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E8282-RJG-2051-chemical-structure.png |