Golidocitinib 1-hydroxy-2-naphthoate
Golidocitinib 1-hydroxy-2-naphthoate is a derivative of Golidocitinib, an oral, potent, selective inhibitor of Janus kinase 1 (JAK1) with an IC50 of 70 nM. It exhibits enhnaced antitumor activity and can be used for the treatment of cancer, including peripheral T cell lymphoma (PTCL).
| Catalog Number | E8276 |
| Molecular Formula | C16H22O10 |
| CAS# | 2091134-68-6(free base) |
| Inchi | InChI=1S/C16H22O10/c17-3-6-1-2-7-8(14(22)23)5-24-15(10(6)7)26-16-13(21)12(20)11(19)9(4-18)25-16/h1,5,7,9-13,15-21H,2-4H2,(H,22,23)/t7-,9-,10-,11-,12+,13-,15+,16+/m1/s1 |
| Inchi Key | ZJDOESGVOWAULF-OGJQONSISA-N |
| SMILES | C1C=C(C2C1C(=COC2OC3C(C(C(C(O3)CO)O)O)O)C(=O)O)CO |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/golidocitinib-1-hydroxy-2-naphthoate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E8276-Golidocitinib-1-hydroxy-2-naphthoate-chemical-structure.png |