L-Asparaginase
L-Asparaginase(L-ASNase) is a deamidating enzyme that hydrolyzes L-asparagine and L-glutamine, depleting L-asparagine in the blood and bone marrow. It exhibits anti-leukemic effects by inhibiting RNA and DNA synthesis, leading to blastic cell apoptosis, and is used in acute lymphoblastic leukemia (ALL) research and treatment.
| Trivial name | L-ASNase |
| Catalog Number | E8190 |
| Molecular Formula | C18H13N3O |
| CAS# | 9015-68-3 |
| Inchi | InChI=1S/C18H13N3O/c22-18-13-6-2-4-8-15(13)20-17-16-12(9-10-21(17)18)11-5-1-3-7-14(11)19-16/h1-8,19H,9-10H2 |
| Inchi Key | ACVGWSKVRYFWRP-UHFFFAOYSA-N |
| SMILES | C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4 |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/l-asparaginase.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8190-l-asparaginase-chemical-structure-tube.png |