PI-103 Hydrochloride
PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy.
Catalog Number | E8147 |
Molecular Formula | C15H10O6 |
CAS# | 371935-79-4 |
Inchi | InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H |
Inchi Key | IQPNAANSBPBGFQ-UHFFFAOYSA-N |
SMILES | C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/pi-103-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/e8147-pi-103-hydrochloride-chemical-structure-tube.png |