NF449 octasodium

NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gsα-selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP[γS] binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of β-adrenergic receptors to Gs.

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Catalog Number	E8096
Molecular Formula	C15H24O5
CAS#	627034-85-9
Inchi	InChI=1S/C15H24O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-13,16H,4-7H2,1-3H3/t8-,9-,10+,11+,12-,13-,14-,15-/m1/s1
Inchi Key	BJDCWCLMFKKGEE-KDTBHNEXSA-N
Size	1mg
Supplier Page	http://www.selleckchem.com/products/nf449-octasodium.html
Additional Information	https://file.selleck.cn/downloads/struct/e8096-nf449-octasodium-chemical-structure-tube.png