BIX02188
BIX02188 is a potent MEK5-selective inhibitor with an IC50 of 4.3 nM. BIX02188 inhibits ERK5 catalytic activity, with an IC50 of 810 nM.
| Catalog Number | E8000 |
| Molecular Formula | C41H43N3O7S |
| CAS# | 334949-59-6 |
| Inchi | InChI=1S/C41H43N3O7S/c45-26-28-17-19-29(20-18-28)35-25-34(27-52-41-43-38(30-11-5-3-6-12-30)39(51-41)31-13-7-4-8-14-31)49-40(50-35)32-21-23-33(24-22-32)42-36(46)15-9-1-2-10-16-37(47)44-48/h3-8,11-14,17 -24,34-35,40,45,48H,1-2,9-10,15-16,25-27H2,(H,42,46)(H,44,47)/t34-,35+,40+/m1/s1 |
| Inchi Key | BHUZLJOUHMBZQY-YXQOSMAKSA-N |
| SMILES | C1C(OC(OC1C2=CC=C(C=C2)CO)C3=CC=C(C=C3)NC(=O)CCCCCCC(=O)NO)CSC4=NC(=C(O4)C5=CC=CC=C5)C6=CC=CC=C6 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/bix02188.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8000-bix02188-chemical-structure-tube.png |